LUC7L3 and CLK1

Number of citations of the paper that reports this interaction (PMID 12565863)
5

Data Source:
HPRD (in vitro)

		LUC7L3	CLK1
Gene Name		LUC7-like 3 (S. cerevisiae)	CDC-like kinase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	DNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity ATP Binding
	Biological Process	MRNA Splice Site Selection RNA Splicing	Cell Proliferation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways
Drugs			Debromohymenialdisine ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CLK1 ITSN2 RNPS1 SRPK1 SRPK2 SRSF1 TLR10 YWHAG	20 interactors: BCLAF1 GOLM1 KRTAP10-7 LUC7L3 MBP NCOR1 PDE9A PIAS4 PPIG PRMT5 PRPF4 PTPN1 SAFB SRPK1 SRPK2 SRSF1 SRSF3 SRSF6 UBL5 YWHAG
Entrez ID		51747	1195
HPRD ID		16759	09058
Ensembl ID		ENSG00000108848	ENSG00000013441
Uniprot IDs		A8K3C5 J3KPP4 O95232 Q86Y74	P49759
PDB IDs			1Z57 2VAG
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Positive Regulation Of Viral Genome Replication MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly MRNA Export From Nucleus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Viral Process MRNA 3'-end Processing Nuclear Speck Organization RNA 3'-end Processing Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death RNA Transport RNA Localization Regulation Of Viral Process Ribonucleoprotein Complex Assembly MRNA 5'-splice Site Recognition Regulation Of Metabolic Process Innate Immune Response Sperm Chromatin Condensation Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cellular Process Ribonucleoprotein Complex Biogenesis MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Immune Response Protein Phosphorylation Regulation Of RNA Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Defense Response Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	RNA Splicing MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Spliceosomal Complex Assembly Ribonucleoprotein Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Ribonucleoprotein Complex Biogenesis Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing RNA 3'-end Processing Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Viral Genome Replication RNA Transport Transcription, DNA-templated RNA Localization RNA Biosynthetic Process Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Speck Organization Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Response To DNA Damage Stimulus Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Viral Genome Replication
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	10q 11q 13q 14q 15q 1q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	10q 11q 13q 14q 15q 1q 21q 2q 3p 3q 4q 6q 8q 9q aberration acsl1 ethnicities gains governing incurable karyotypes lyst malaysia malaysian myeloma nfkbia penetrance predispositions xq
Tagcloud (Intersection) ?