LUC7L3

Description		LUC7 like 3 pre-mRNA splicing factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splice Site Recognition MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Mild to moderate chronic kidney disease ( 31178898)
Interacting Genes		12 interacting genes: CLK1 ITSN2 MLH1 OGT RNPS1 SRPK1 SRPK2 SRSF1 TLR10 TXNIP USP7 YWHAG
Entrez ID		51747
HPRD ID		16759
Ensembl ID		ENSG00000108848
Uniprot IDs		A8K3C5 J3KPP4 O95232 Q86Y74
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing TORC1 Signaling TOR Signaling MRNA Metabolic Process Regulation Of TORC1 Signaling Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Exon-exon Junction Complex RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of TOR Signaling Nuclear Speck MRNA Processing Positive Regulation Of Viral Genome Replication Response To Stress Protein-RNA Complex Assembly Regulation Of Macromolecule Metabolic Process Signal Transduction Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Intracellular Signal Transduction Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Gene Expression Cellular Response To Nutrient Levels Regulation Of Gluconeogenesis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Localization To Organelle Protein Localization To Lysosome Regulation Of Metabolic Process Positive Regulation Of Viral Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Gene Expression Chromosome Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment
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