PARP1 and HDAC1

  • Number of citations of the paper that reports this interaction (PMID 19470756)
  • 55
  • Data Source:
  • BioGRID (enzymatic study)

PARP1

HDAC1

Gene Name poly (ADP-ribose) polymerase 1 histone deacetylase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423 193 interactors: APEX1 APPL1 AR ARHGAP35 ARID4A ATF3 ATRX BAZ2A BCL3 BCL6B BCOR BHLHE40 BRCA1 BRMS1 BRMS1L BUB1 BUB1B BUB3 CBFA2T3 CDC20 CDH1 CDKN1A CDYL CHD1 CHD4 CHFR CIITA CNTN2 CREBBP CREM CSNK2A1 CSNK2A2 CTBP1 DAXX DDB2 DDX17 DHX30 DNMT1 DNMT3A DNMT3B DNMT3L EED EID2 EID2B ELK1 ENO1 EP300 EZH2 FKBP3 FOXG1 FRA10F GATAD2A GATAD2B GCM1 GMNN GPS2 HBP1 HDAC2 HDAC3 HDAC7 HDAC9 HELLS HEY2 HIC1 HIF1A HIF1AN HIST1H4A HIST3H3 HNRNPD HR HUS1 IKZF1 ING1 IRF5 JDP2 KAT5 KCTD11 KDM1A KLF1 KLF11 KLF4 KLF5 LCOR LINC00152 MAD1L1 MAGEA1 MBD2 MBD3 MBD3L2 MBD4 MCM6 MDM2 MECOM MECP2 MEN1 MIER1 MORF4L2 MTA1 MXD1 MYOD1 NCOR2 NFE4 NFKB1 NFKBIA NKX2-5 NKX3-2 NR1D2 NR2E3 NR2F2 NRIP1 NUP98 PARP1 PCNA PEX14 PHB PHB2 PHF12 PHF21A PIAS3 PIAS4 PIK3R1 PITX2 PLK4 PML PPARD PPARG PPP2R1B PRKACA PRKG1 PRRG4 PTMA RAD9A RAP1A RARA RB1 RBBP4 RBBP7 RBL1 RBL2 RBP1 RBPJ RELA REPIN1 RFC1 RFC4 RICTOR RUNX1 RUNX1T1 RUNX3 RUVBL1 RUVBL2 SALL1 SAP18 SAP30 SATB1 SATB2 SENP1 SET SETDB1 SIN3A SIN3B SMAD2 SMAD3 SOX6 SP1 SP3 SPEN SPI1 STAT2 STAT3 SUDS3 SUV39H1 SYK TAB2 TAL1 TFCP2 TGIF1 TGIF2 THAP11 TOP2A TOP2B TP53 TPD52L1 TRIM27 TXNIP UBE2I UHRF2 VHL VPRBP WISP2 ZBTB16 ZMYND11 ZNF76
Entrez ID 142 3065
HPRD ID 01435 03143
Ensembl ID ENSG00000143799 ENSG00000116478
Uniprot IDs P09874 Q13547 Q6IT96
PDB IDs 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S 1TYI 4BKX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
bhlh  complexes  corepressors  deacetylase  deacetylation  heterodimerize  heterodimers  heterogeneous  immunocomplexes  mad  max  mediates  members  msin3a  msin3b  multimeric  multiprotein  p50  p55  polypeptides  possess  reporter  repress  repression  ternary  tightly  transcriptional  trapoxin  zip 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
bhlh  complexes  corepressors  deacetylase  deacetylation  heterodimerize  heterodimers  heterogeneous  immunocomplexes  mad  max  mediates  members  msin3a  msin3b  multimeric  multiprotein  p50  p55  polypeptides  possess  reporter  repress  repression  ternary  tightly  transcriptional  trapoxin  zip 
Tagcloud (Intersection) ?