PARP1 and MED14

  • Number of citations of the paper that reports this interaction (PMID 16204234)
  • 61
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

PARP1

MED14

Gene Name poly (ADP-ribose) polymerase 1 mediator complex subunit 14
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423 20 interactors: ACTN1 ACTN2 AR CTDP1 DCTN1 ESR1 ESR2 HNF4A MED1 MED29 MED9 MYC NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR
Entrez ID 142 9282
HPRD ID 01435 02172
Ensembl ID ENSG00000143799 ENSG00000180182
Uniprot IDs P09874 O60244
PDB IDs 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
bridges  cha1  eliminated  eukaryotes  gal11  kin28  machinery  med15  med17  med18  mediator  module  modules  paf1  rbp1  recruitment  remodeling  rgr1  ser2  ser5  severely  snf  srb4  srb5  swi  tata  tbp  ts  unaffected 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
bridges  cha1  eliminated  eukaryotes  gal11  kin28  machinery  med15  med17  med18  mediator  module  modules  paf1  rbp1  recruitment  remodeling  rgr1  ser2  ser5  severely  snf  srb4  srb5  swi  tata  tbp  ts  unaffected 
Tagcloud (Intersection) ?