SMAD2 and PIAS4

  • Number of citations of the paper that reports this interaction (PMID 12904571)
  • 24
  • Data Source:
  • HPRD (in vivo, two hybrid)

SMAD2

PIAS4

Gene Name SMAD family member 2 protein inhibitor of activated STAT, 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 207 interactors: ABTB1 ACVR1B AKT1 ANAPC10 ANAPC2 ANK3 ANP32B ANP32E ANTXR2 AP1B1 ARFGAP3 ARHGEF6 ARL4D ATP5I AXIN1 BAZ1A BPTF BRCA1 BTBD2 C22orf46 CAMK2A CAMK2G CDC16 CDC27 CDC40 CDK2 CDK4 CDK8 CDK9 CISH COPS5 CREBBP CSH1 CSH2 CSNK1D CTNNB1 CUL5 CYP11A1 DAB2 DCAF6 DCUN1D1 DNAJC7 DOCK8 DVL1 DYNC1H1 E2F4 EEF1A1 EID2 EIF3L ELAC2 EP300 ERBB2IP ESR1 ESR2 FAM161B FBN2 FHL2 FHL3 FOXG1 FOXH1 FOXO3 GATAD2B GFER GLI3 GRIPAP1 GSC GTF2I HDAC1 HDAC2 HGS HIPK2 HNF4A HOXA13 HOXA9 HOXD13 HUWE1 INSR IRAK2 ITCH JUN KAT2B KHDRBS1 KIAA1033 KPNB1 LAMA5 LCK LEF1 LEMD3 LHX9 LITAF LMO2 MAPK1 MAPK3 MAPK8 MAPK9 MECOM MED15 MED6 MEF2A MEF2C MLLT4 MYC MYOCD NAGK NCOA6 NEDD4L NEDD9 NEFM NF1 NFYC NOTCH4 NUAK2 NUP153 NUP214 OS9 OTUB1 PAK1 PAPOLA PAPPA PARD3 PARD3B PAXIP1 PEX19 PIAS3 PIAS4 PIK3CA PLIN3 POU2AF1 PPM1A PPP2R1A PRKAR1A PSAP PSG9 PSMD11 PSMD8 PTMS RAB34 RAB38 RAN RANBP6 RANBP9 RARB RASD2 RASL12 RBL1 RHEBL1 RHOA RHOD RHOJ RIT1 RNF123 RNPC3 ROCK1 RPS14 RPS27A RUNX2 RXRA SKI SKIL SKOR2 SMAD1 SMAD3 SMAD4 SMAD7 SMAD9 SMURF1 SMURF2 SNAPIN SNIP1 SNRNP70 SNW1 SOD1 SP1 SQSTM1 SRI ST13 ST5 STAG1 STAMBP STAMBPL1 STRAP STUB1 SYT1 TBC1D1 TGFBR1 TGFBRAP1 TGIF1 TGM2 TNNT1 TOB1 TP53 TP73 TRIM62 TSC2 TUBA1B UBA52 UBR5 UCHL5 USP9X YY1 ZEB1 ZEB2 ZFYVE9 ZMYND11 ZNF41 ZNF8 ZNHIT6 75 interactors: ACTN1 ALDOA AR BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TP53 TRIM27 TRIM32 UBE2I UBE2K VIM ZHX1 ZNF512B
Entrez ID 4087 51588
HPRD ID 03221 06910
Ensembl ID ENSG00000175387
Uniprot IDs B7Z5N5 Q15796 Q53XR6 Q8N2W9
PDB IDs 1DEV 1KHX 1U7V 2LB3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenoviral  cbp  coactivators  e1a  enhancement  fashion  interacted  interacting  intrinsic  lux  mapped  mediating  minimal  oncoprotein  p300  p3tp  possess  possibility  raise  regulators  rest  signalling  smad3  smads  superfamily  tgf  transactivation  transforming 
acceptor  acetyltransferase  alignment  consensus  consequently  deacetylase  dgcr8  e195a  e3  ing  ing1  ing1b  ing2  ing3  ings  isg15  k193  ligase  marks  mislocalized  pdsm  phosphomimic  preferred  reveals  s199d  stoichiometric  sumo  sumoylation  suppressors 
Tagcloud (Difference) ?
adenoviral  cbp  coactivators  e1a  enhancement  fashion  interacted  interacting  intrinsic  lux  mapped  mediating  minimal  oncoprotein  p300  p3tp  possess  possibility  raise  regulators  rest  signalling  smad3  smads  superfamily  tgf  transactivation  transforming 
acceptor  acetyltransferase  alignment  consensus  consequently  deacetylase  dgcr8  e195a  e3  ing  ing1  ing1b  ing2  ing3  ings  isg15  k193  ligase  marks  mislocalized  pdsm  phosphomimic  preferred  reveals  s199d  stoichiometric  sumo  sumoylation  suppressors 
Tagcloud (Intersection) ?