JAK1 and STAT6

  • Number of citations of the paper that reports this interaction (PMID 10856136)
  • 50
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

JAK1

STAT6

Gene Name Janus kinase 1 signal transducer and activator of transcription 6, interleukin-4 induced
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2 37 interactors: ANKZF1 ANXA2 CEBPB CEBPE CEBPZ CREBBP DAZAP2 EEF1A1 EP300 ETS1 HIST2H3C IFNG IL4R IRF4 JAK1 LITAF NCOA1 NCOA2 NFKB1 NMI PPARG PRKCZ PTPN6 RCN3 RELA RLIM SND1 SRC STAT2 STAT3 TP53 TRIM24 VKORC1 WWP1 ZBTB2 ZNF407 ZNF92
Entrez ID 3716 6778
HPRD ID 00992 03302
Ensembl ID ENSG00000162434 ENSG00000166888
Uniprot IDs P23458 A8K4S9 B4DQB3 P42226
PDB IDs 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01 1OJ5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
13r  13ralpha  2rgammac  4r  alternative  chains  classical  consist  consists  crucial  exist  form  forms  gammac  hand  hematopoietic  il  instead  jak1  jak3  lack  predominantly  recently  regard  signals  transduction  transmitted  tyrosine  utilized 
Tagcloud (Difference) ?
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
13r  13ralpha  2rgammac  4r  alternative  chains  classical  consist  consists  crucial  exist  form  forms  gammac  hand  hematopoietic  il  instead  jak3  lack  predominantly  recently  regard  signals  transduction  transmitted  tyrosine  utilized 
Tagcloud (Intersection) ?
jak1