ILF2 and SREK1

Number of citations of the paper that reports this interaction (PubMedID 14559993)
73

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		ILF2	SREK1
Description		interleukin enhancer binding factor 2	splicing regulatory glutamic acid and lysine rich protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Specific Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Positive Regulation Of DNA-templated Transcription	MRNA Processing RNA Splicing
Pathways		Neutrophil degranulation PKR-mediated signaling
Drugs
Diseases
GWAS			Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		22 interacting genes: CCNDBP1 CEBPA DYNLT1 EEF1G EIF2AK2 EP300 ERG EXOSC8 H19 IL7R INCA1 IQGAP1 KRTAP6-3 MEOX2 OGT PICK1 PRKDC PTEN SGSM2 SREK1 TRIM27 ZMYND12	66 interacting genes: ARL6IP4 CD8A CKAP2 CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 MRPL37 NAT10 NCL NPM1 PABPC1 PABPC4 PARP1 PCBP3 PIN1 PRPF40A RAB5C RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRRM4 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		3608	140890
HPRD ID		04419	18043
Ensembl ID		ENSG00000143621	ENSG00000153914
Uniprot IDs		B4DY09 F4ZW62 Q12905 Q53FG3	Q8WXA9
PDB IDs
Enriched GO Terms of Interacting Partners?		STAT Family Protein Binding Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphate Metabolic Process Protein Domain Specific Binding Chromatin DNA Binding Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Differentiation Positive Regulation Of Biosynthetic Process Leukocyte Differentiation Nucleoplasm Defense Response Positive Regulation Of RNA Biosynthetic Process Response To Nutrient Levels Positive Regulation Of Gene Expression Regulation Of Cell Development Negative Regulation Of Cell Cycle Cell Development Mononuclear Cell Differentiation Positive Regulation Of DNA-templated Transcription RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Cytoplasm Protein Modification Process T Cell Lineage Commitment Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-lysine Propionylation Histone Acetyltransferase Complex Protein-DNA Complex Regulation Of Protein Modification Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Lymphocyte Differentiation Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Cellular Response To Nutrient Levels Circadian Rhythm Histone Crotonyltransferase Activity Rhythmic Process Phosphorylation Protein Phosphorylation T Cell Differentiation In Thymus Neuron Projection Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Phosphorylation	RNA Splicing RNA Binding MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding Regulation Of RNA Splicing RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Binding Nuclear Speck Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal Complex Ribonucleoprotein Complex Nucleoplasm Nucleus Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Primary Metabolic Process MRNA Stabilization Regulation Of Gene Expression Spliceosomal Complex Assembly Protein-RNA Complex Assembly Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Alternative MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Pre-mRNA Binding Negative Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?