ILF2 and H19

Number of citations of the paper that reports this interaction (PubMedID 37298108)
45

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		ILF2	H19
Description		interleukin enhancer binding factor 2	H19 imprinted maternally expressed transcript
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Specific Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding
	Biological Process	Positive Regulation Of DNA-templated Transcription
Pathways		Neutrophil degranulation PKR-mediated signaling
Drugs
Diseases			Russell-Silver syndrome; Silver-Russell syndrome Beckwith-Wiedemann syndrome
GWAS			Celiac disease ( 23936387) Creatinine levels ( 29403010) Diastolic blood pressure ( 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) DNA methylation (parent-of-origin) ( 23725790) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 30487518) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27841878 28135244) Systolic blood pressure (cigarette smoking interaction) ( 29455858)
Interacting Genes		22 interacting genes: CCNDBP1 CEBPA DYNLT1 EEF1G EIF2AK2 EP300 ERG EXOSC8 H19 IL7R INCA1 IQGAP1 KRTAP6-3 MEOX2 OGT PICK1 PRKDC PTEN SGSM2 SREK1 TRIM27 ZMYND12	21 interacting genes: BCLAF1 DDX5 DSP ESRP1 FMR1 IFIT5 ILF2 MYO1D NSD2 PCCA PCCB PPP1R3E PRKRA SERBP1 SRSF10 SRSF8 SRSF9 SSB STON2 TPM1 U2SURP
Entrez ID		3608	283120
HPRD ID		04419
Ensembl ID		ENSG00000143621	ENSG00000130600
Uniprot IDs		B4DY09 F4ZW62 Q12905 Q53FG3
PDB IDs
Enriched GO Terms of Interacting Partners?		STAT Family Protein Binding Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphate Metabolic Process Protein Domain Specific Binding Chromatin DNA Binding Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Differentiation Positive Regulation Of Biosynthetic Process Leukocyte Differentiation Nucleoplasm Defense Response Positive Regulation Of RNA Biosynthetic Process Response To Nutrient Levels Positive Regulation Of Gene Expression Regulation Of Cell Development Negative Regulation Of Cell Cycle Cell Development Mononuclear Cell Differentiation Positive Regulation Of DNA-templated Transcription RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Cytoplasm Protein Modification Process T Cell Lineage Commitment Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-lysine Propionylation Histone Acetyltransferase Complex Protein-DNA Complex Regulation Of Protein Modification Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Lymphocyte Differentiation Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Cellular Response To Nutrient Levels Circadian Rhythm Histone Crotonyltransferase Activity Rhythmic Process Phosphorylation Protein Phosphorylation T Cell Differentiation In Thymus Neuron Projection Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Phosphorylation	RNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Binding Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Processing Propionyl-CoA Carboxylase Activity Regulation Of MRNA Metabolic Process Poly(U) RNA Binding RNA Splicing MRNA Metabolic Process MRNA Processing Short-chain Fatty Acid Catabolic Process Ribonucleoprotein Complex SiRNA Binding Sequence-specific MRNA Binding Nuclear Speck Translation Repressor Activity Short-chain Fatty Acid Metabolic Process Nuclear-transcribed MRNA Catabolic Process Negative Regulation Of Gene Expression Regulation Of Viral Life Cycle Catalytic Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Branched-chain Amino Acid Metabolic Process MRNA Catabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Regulation Of Viral Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus MRNA Splice Site Recognition MiRNA Processing Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process MiRNA Transcription Positive Regulation Of Intracellular Transport Of Viral Material Ligase Activity, Forming Carbon-carbon Bonds Nuclear Histone MRNA Catabolic Process Positive Regulation Of Heart Rate By Epinephrine Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Primary Metabolic Process RNA Catabolic Process Nucleic Acid Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Macromolecule Metabolic Process
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