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PACSIN3 and TERF2IP
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
PACSIN3
TERF2IP
Gene Name
protein kinase C and casein kinase substrate in neurons 3
telomeric repeat binding factor 2, interacting protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Endosome
Plasma Membrane
Membrane
Membrane-bounded Vesicle
Extracellular Vesicular Exosome
Nuclear Chromosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nuclear Chromosome, Telomeric Region
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mre11 Complex
Molecular Function
Protein Binding
Phospholipid Binding
Cytoskeletal Protein Binding
Lipid Binding
Calcium Channel Inhibitor Activity
Protein Binding
Telomeric DNA Binding
Biological Process
Endocytosis
Cytoskeleton Organization
Regulation Of Endocytosis
Negative Regulation Of Endocytosis
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Calcium Ion Transport
Membrane Tubulation
Telomere Maintenance
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Telomere Maintenance Via Telomerase
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Telomere Maintenance
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Chromosome, Telomeric Region
Pathways
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ADAM12
ADAM15
ASAP1
ASAP2
DNM1
ITSN1
LGALS13
PACSIN1
PACSIN2
PAK2
RAF1
SOS1
SOS2
SPRY2
SYNJ1
TERF2IP
TRPV4
WASL
125 interactors:
ADA
AIMP2
AK1
AKR1A1
AKR1B10
AKR7A3
AKT1
ANXA5
AP2B1
APEX1
ARPP21
BABAM1
BANP
BCL7B
C1orf174
C9orf78
CALML3
CHMP2B
COTL1
CPNE2
CPNE3
CRK
CRYBB1
CRYGS
CTBP1
DBNL
DDX23
DDX24
DDX39A
DHX38
DNMT3A
DPP3
ENAH
EPAS1
EPS8L1
FABP2
FAM122A
GAGE5
GAMT
GNMT
GPKOW
HAAO
HAGH
HDGFRP3
HIST1H1A
HIST1H2AL
HIST1H4B
HMGB1
HMGB3
HMGN3
HMGN4
HNRNPK
IDO1
IL1RN
LANCL2
LGALSL
MAGOHB
MCM2
MDH1
MPG
MRTO4
MT1X
MT3
NAIF1
NASP
NOL3
NUDT14
NUDT18
NUMA1
NXNL1
OCM2
OGFR
PACSIN2
PACSIN3
PAFAH1B3
PCNP
PCP4
PEA15
PGLS
PGM1
PML
PNMT
POLD1
PPM1G
PPP1R2
PPP6R3
PRDX6
PRX
PTMA
RABIF
RAD50
RASSF5
RBBP9
RECQL4
RGMA
RIF1
RPAP1
RPP25
S100P
SBDS
SCLY
SCRN2
SET
SMARCC2
SNCG
SP100
TALDO1
TBC1D10A
TBCA
TERF2
TMSB10
TMSB4Y
TOR1AIP1
TSSC4
TWF2
UCHL1
VGLL4
WDR5
WIPI2
XAGE2
XPO1
XRCC5
XRCC6
ZNF146
ZNF414
Entrez ID
29763
54386
HPRD ID
05937
05452
Ensembl ID
ENSG00000165912
ENSG00000166848
Uniprot IDs
Q9UKS6
Q9NYB0
PDB IDs
1FEX
3K6G
Enriched GO Terms of Interacting Partners
?
Cell Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Cell Projection Organization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Guidance
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Development
Regulation Of Ras Protein Signal Transduction
Anatomical Structure Development
Cell Differentiation
Generation Of Neurons
Regulation Of Small GTPase Mediated Signal Transduction
Neuron Differentiation
Neurogenesis
Developmental Process
Regulation Of Ras GTPase Activity
Synaptic Vesicle Endocytosis
Cell Development
Synaptic Vesicle Recycling
Establishment Of Organelle Localization
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Endocytosis
Organelle Localization
Establishment Of Vesicle Localization
Nervous System Development
Regulation Of GTPase Activity
Vesicle Localization
Neurotrophin TRK Receptor Signaling Pathway
Signaling
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Catalytic Activity
Locomotion
Regulation Of Signaling
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cell Communication
Cell Surface Receptor Signaling Pathway
Chromosome Organization
Telomere Maintenance
Cellular Nitrogen Compound Metabolic Process
Organelle Organization
Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Chromatin Organization
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
DNA Conformation Change
Chromatin Modification
Cell Cycle
Cellular Response To Stress
DNA Metabolic Process
Cellular Response To DNA Damage Stimulus
Sequestering Of Actin Monomers
DNA Recombination
Telomere Maintenance Via Telomere Lengthening
Catabolic Process
DNA Duplex Unwinding
Cellular Aldehyde Metabolic Process
Cellular Hyperosmotic Salinity Response
DNA Geometric Change
DNA Replication
Energy Reserve Metabolic Process
Nucleosome Organization
Organophosphate Catabolic Process
Response To Stress
Chromatin Assembly Or Disassembly
Deoxyribose Phosphate Catabolic Process
Cellular Localization
Cellular Metabolic Process
Protein Localization To Nucleus
Glycogen Metabolic Process
Nucleocytoplasmic Transport
Chromatin Remodeling
Base-excision Repair
Cellular Response To X-ray
Nuclear Transport
Aromatic Compound Catabolic Process
Nucleosome Assembly
Deoxyribonucleotide Catabolic Process
DNA Strand Elongation Involved In DNA Replication
Small Molecule Metabolic Process
DNA Strand Elongation
Biosynthetic Process
Chromatin Assembly
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Transport
Energy Derivation By Oxidation Of Organic Compounds
Tagcloud
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
tinf
tinf2
yates
Tagcloud (Difference)
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
tinf
tinf2
yates
Tagcloud (Intersection)
?