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TERF2IP and IDO1
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TERF2IP
IDO1
Description
TERF2 interacting protein
indoleamine 2,3-dioxygenase 1
Image
GO Annotations
Cellular Component
Nuclear Chromosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Nuclear Body
Shelterin Complex
Cytoplasm
Cytosol
Smooth Muscle Contractile Fiber
Stereocilium Bundle
Molecular Function
Protein Binding
Phosphatase Binding
Telomeric DNA Binding
G-rich Strand Telomeric DNA Binding
Tryptophan 2,3-dioxygenase Activity
Electron Transfer Activity
Oxidoreductase Activity
Heme Binding
Indoleamine 2,3-dioxygenase Activity
Metal Ion Binding
Dioxygenase Activity
Biological Process
Telomere Maintenance
Negative Regulation Of Protein Phosphorylation
Regulation Of DNA-templated Transcription
Telomere Maintenance Via Telomerase
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Telomere Capping
Protection From Non-homologous End Joining At Telomere
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Telomere Maintenance
Intracellular Signal Transduction
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Chromosome, Telomeric Region
Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Immune System Process
Positive Regulation Of T Cell Tolerance Induction
Positive Regulation Of Chronic Inflammatory Response
Positive Regulation Of Type 2 Immune Response
L-tryptophan Catabolic Process
Inflammatory Response
Female Pregnancy
L-tryptophan Catabolic Process To Kynurenine
Quinolinate Biosynthetic Process
Response To Lipopolysaccharide
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Multicellular Organismal Response To Stress
Kynurenic Acid Biosynthetic Process
'de Novo' NAD+ Biosynthetic Process From L-tryptophan
Swimming Behavior
T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Positive Regulation Of Apoptotic Process
Regulation Of Activated T Cell Proliferation
Negative Regulation Of T Cell Apoptotic Process
Positive Regulation Of T Cell Apoptotic Process
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Tryptophan catabolism
Drugs
Nitric Oxide
Cannabidiol
Medical Cannabis
Nabiximols
Diseases
GWAS
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Smoking status (ever vs never smokers) (
30643258
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Weight (
34074324
)
Interacting Genes
122 interacting genes:
ADA
AIMP2
AK1
AKR1A1
AKR1B10
AKR7A3
AKT1
ANXA5
ANXA8L1
AP2B1
APEX1
ARPP21
BABAM1
BANP
BCL7B
C1orf174
CALML3
CHMP2B
COTL1
CPNE2
CPNE3
CRK
CRYBB1
CRYGS
CTBP1
DBNL
DDX23
DDX24
DDX39A
DNMT3A
DPP3
ENAH
EPAS1
EPS8L1
ETS2
FABP2
GAGE5
GAMT
GNMT
H1-1
H2AC16
H4C2
HAAO
HAGH
HDGFL3
HMGB1
HMGB3
HMGN3
HMGN4
HNRNPK
IDO1
IL1RN
LANCL2
LGALSL
MAGOHB
MCM2
MDH1
MPG
MRTO4
MT1X
MT3
NAIF1
NASP
NOL3
NPSR1
NUDT14
NUDT18
NXNL1
OCM2
OGFR
PABIR1
PACSIN2
PACSIN3
PAFAH1B3
PCNP
PCP4
PEA15
PGLS
PGM1
PIAS1
PML
PNMT
PPP1R2
PPP6R3
PRDX6
PRX
PTEN
PTMA
RABIF
RAD50
RASSF5
RBBP9
RECQL4
RGMA
RIF1
RPAP1
RPP25
S100P
SBDS
SCLY
SCRN2
SET
SNCG
SP100
TALDO1
TBC1D10A
TBCA
TERF2
TMSB10
TMSB4Y
TOR1AIP1
TSSC4
TWF2
UCHL1
VGLL4
WDR5
WIPI2
XAGE2
XPO1
XRCC5
ZNF146
ZNF414
5 interacting genes:
APP
DDX24
FBXL17
PPP1R16A
TERF2IP
Entrez ID
54386
3620
HPRD ID
05452
00935
Ensembl ID
ENSG00000166848
ENSG00000131203
Uniprot IDs
Q9NYB0
A0A348GSI3
P14902
PDB IDs
1FEX
3K6G
4RQI
7OZ0
8RD4
2D0T
2D0U
4PK5
4PK6
4U72
4U74
5EK2
5EK3
5EK4
5ETW
5WHR
5WMU
5WMV
5WMW
5WMX
5WN8
5XE1
6AZU
6AZV
6AZW
6CXU
6CXV
6DPQ
6DPR
6E35
6E40
6E41
6E42
6E43
6E44
6E45
6E46
6F0A
6KOF
6KPS
6KW7
6MQ6
6O3I
6PU7
6PZ1
6R63
6UBP
6V52
6WJY
6WPE
6X5Y
7A62
7AH4
7AH5
7AH6
7B1O
7E0O
7E0P
7E0Q
7E0S
7E0T
7E0U
7M63
7M7D
7NGE
7P0N
7P0R
7RRB
7RRC
7RRD
7YXT
7Z2L
7ZV3
8ABX
8FUR
8I7L
8U5I
9ESB
9ESC
9ESE
9ESG
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Protein Binding
Cytosol
Double-stranded Telomeric DNA Binding
Nucleobase-containing Compound Metabolic Process
Chromatin Organization
Chromosome, Telomeric Region
Telomere Organization
Chromatin Remodeling
Protein Domain Specific Binding
Nucleus
Telomere Maintenance
Nucleoplasm
Energy Reserve Metabolic Process
Chromosome Organization
Glycogen Metabolic Process
Alcohol Dehydrogenase (NADP+) Activity
Cellular Detoxification Of Aldehyde
Extracellular Exosome
Telomere Maintenance In Response To DNA Damage
Myelin Maintenance
Negative Regulation Of T-circle Formation
Polysaccharide Metabolic Process
Nucleic Acid Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Maintenance Of Protein Localization In Organelle
DNA Metabolic Process
Plasma Membrane Organization
Quinolinate Biosynthetic Process
Allyl-alcohol Dehydrogenase Activity
DNA Recombination
Helicase Activity
Regulation Of Growth
Generation Of Precursor Metabolites And Energy
Calcium-dependent Phospholipid Binding
Negative Regulation Of DNA Metabolic Process
Cadherin Binding
Regulation Of Cellular Response To Stress
Quinolinate Metabolic Process
Mre11 Complex
Negative Regulation Of Cellular Component Organization
Carbohydrate Metabolic Process
Regulation Of Cell Growth
Actin Monomer Binding
Positive Regulation Of Proteolysis
Maintenance Of Protein Location In Cell
RNA-templated DNA Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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