TERF2IP and TOR1AIP1

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		TERF2IP	TOR1AIP1
Gene Name		telomeric repeat binding factor 2, interacting protein	torsin A interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mre11 Complex	Nucleus Nuclear Inner Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Telomeric DNA Binding	ATPase Activator Activity Lamin Binding Cytoskeletal Protein Binding ATPase Binding
	Biological Process	Telomere Maintenance Transcription, DNA-templated Regulation Of Transcription, DNA-templated Telomere Maintenance Via Telomerase Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance Via Telomere Lengthening Protection From Non-homologous End Joining At Telomere Negative Regulation Of Telomere Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Chromosome, Telomeric Region	Positive Regulation Of ATPase Activity Protein Localization To Nucleus Nuclear Membrane Organization
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		125 interactors: ADA AIMP2 AK1 AKR1A1 AKR1B10 AKR7A3 AKT1 ANXA5 AP2B1 APEX1 ARPP21 BABAM1 BANP BCL7B C1orf174 C9orf78 CALML3 CHMP2B COTL1 CPNE2 CPNE3 CRK CRYBB1 CRYGS CTBP1 DBNL DDX23 DDX24 DDX39A DHX38 DNMT3A DPP3 ENAH EPAS1 EPS8L1 FABP2 FAM122A GAGE5 GAMT GNMT GPKOW HAAO HAGH HDGFRP3 HIST1H1A HIST1H2AL HIST1H4B HMGB1 HMGB3 HMGN3 HMGN4 HNRNPK IDO1 IL1RN LANCL2 LGALSL MAGOHB MCM2 MDH1 MPG MRTO4 MT1X MT3 NAIF1 NASP NOL3 NUDT14 NUDT18 NUMA1 NXNL1 OCM2 OGFR PACSIN2 PACSIN3 PAFAH1B3 PCNP PCP4 PEA15 PGLS PGM1 PML PNMT POLD1 PPM1G PPP1R2 PPP6R3 PRDX6 PRX PTMA RABIF RAD50 RASSF5 RBBP9 RECQL4 RGMA RIF1 RPAP1 RPP25 S100P SBDS SCLY SCRN2 SET SMARCC2 SNCG SP100 TALDO1 TBC1D10A TBCA TERF2 TMSB10 TMSB4Y TOR1AIP1 TSSC4 TWF2 UCHL1 VGLL4 WDR5 WIPI2 XAGE2 XPO1 XRCC5 XRCC6 ZNF146 ZNF414	7 interactors: LMNA LMNB1 PPP1CA PPP1CC TERF2 TERF2IP TOR1A
Entrez ID		54386	26092
HPRD ID		05452	13958
Ensembl ID		ENSG00000166848	ENSG00000143337
Uniprot IDs		Q9NYB0	Q5JTV8
PDB IDs		1FEX 3K6G
Enriched GO Terms of Interacting Partners?		Chromosome Organization Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Organelle Organization Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process DNA Conformation Change Chromatin Modification Cell Cycle Cellular Response To Stress DNA Metabolic Process Cellular Response To DNA Damage Stimulus Sequestering Of Actin Monomers DNA Recombination Telomere Maintenance Via Telomere Lengthening Catabolic Process DNA Duplex Unwinding Cellular Aldehyde Metabolic Process Cellular Hyperosmotic Salinity Response DNA Geometric Change DNA Replication Energy Reserve Metabolic Process Nucleosome Organization Organophosphate Catabolic Process Response To Stress Chromatin Assembly Or Disassembly Deoxyribose Phosphate Catabolic Process Cellular Localization Cellular Metabolic Process Protein Localization To Nucleus Glycogen Metabolic Process Nucleocytoplasmic Transport Chromatin Remodeling Base-excision Repair Cellular Response To X-ray Nuclear Transport Aromatic Compound Catabolic Process Nucleosome Assembly Deoxyribonucleotide Catabolic Process DNA Strand Elongation Involved In DNA Replication Small Molecule Metabolic Process DNA Strand Elongation Biosynthetic Process Chromatin Assembly Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Transport Energy Derivation By Oxidation Of Organic Compounds	Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Protein Localization To Organelle Regulation Of Telomere Maintenance Triglyceride Catabolic Process RNA-dependent DNA Replication Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Glycogen Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Nuclear Envelope Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Execution Phase Of Apoptosis Telomere Maintenance Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Negative Regulation Of Chromosome Organization Sterol Regulatory Element Binding Protein Import Into Nucleus Negative Regulation Of DNA Recombination At Telomere Cell Cycle Cellular Protein Localization Triglyceride Metabolic Process Regulation Of Circadian Rhythm Negative Regulation Of DNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Nucleus Organization Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Signaling Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Telomeric Loop Formation Positive Regulation Of Synaptic Vesicle Endocytosis Age-dependent Telomere Shortening ER-associated Misfolded Protein Catabolic Process Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Protein Localization To Nucleus Circadian Rhythm
Tagcloud ?		acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 tinf tinf2 yates	dephosphorylated dreifuss dystonia dystrophy dyt1 emerin emery envelope integral isoform isoforms lamina lamins lap1 lap1a lap1b lap1c methionine muscular originate permitted pp1 putatively silico torsina translationally ubiquitously undergoes unraveled
Tagcloud (Difference) ?		acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 tinf tinf2 yates	dephosphorylated dreifuss dystonia dystrophy dyt1 emerin emery envelope integral isoform isoforms lamina lamins lap1 lap1a lap1b lap1c methionine muscular originate permitted pp1 putatively silico torsina translationally ubiquitously undergoes unraveled
Tagcloud (Intersection) ?