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PACSIN3 and DNM1
Number of citations of the paper that reports this interaction (PMID
11082044
)
39
Data Source:
HPRD
(in vitro, two hybrid)
PACSIN3
DNM1
Gene Name
protein kinase C and casein kinase substrate in neurons 3
dynamin 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Endosome
Plasma Membrane
Membrane
Membrane-bounded Vesicle
Extracellular Vesicular Exosome
Microtubule
Plasma Membrane
Membrane Coat
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Phospholipid Binding
Cytoskeletal Protein Binding
Lipid Binding
Calcium Channel Inhibitor Activity
GTPase Activity
Protein Binding
GTP Binding
Protein C-terminus Binding
Protein Kinase Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Nitric-oxide Synthase Binding
Biological Process
Endocytosis
Cytoskeleton Organization
Regulation Of Endocytosis
Negative Regulation Of Endocytosis
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Calcium Ion Transport
Membrane Tubulation
Endocytosis
Receptor-mediated Endocytosis
Endosome Organization
Axon Guidance
Receptor Internalization
Ephrin Receptor Signaling Pathway
Clathrin-mediated Endocytosis
Pathways
Retrograde neurotrophin signalling
Signalling by NGF
Formation of annular gap junctions
Axon guidance
Gap junction degradation
Gap junction trafficking
L1CAM interactions
NGF signalling via TRKA from the plasma membrane
Recycling pathway of L1
Toll-Like Receptors Cascades
EPH-ephrin mediated repulsion of cells
Toll Like Receptor 4 (TLR4) Cascade
Gap junction trafficking and regulation
MHC class II antigen presentation
EPH-Ephrin signaling
Adaptive Immune System
Innate Immune System
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
18839057
)
Protein-Protein Interactions
18 interactors:
ADAM12
ADAM15
ASAP1
ASAP2
DNM1
ITSN1
LGALS13
PACSIN1
PACSIN2
PAK2
RAF1
SOS1
SOS2
SPRY2
SYNJ1
TERF2IP
TRPV4
WASL
47 interactors:
AMPH
AP2A2
ASB13
BIN1
CABIN1
CAV1
CDK5
CLIC3
CLIC4
CLINT1
CTTN
DNM2
DNMBP
EPS15
FNBP1
GNB2L1
GRB2
GRIN1
GRIN2D
ITSN1
KIAA1377
MAP3K10
MED31
MOB4
NCK1
NCK2
NME2
PACSIN1
PACSIN2
PACSIN3
PFN2
PIAS1
PIK3R1
PIN4
PLCG1
PRKCA
PRNP
SH3GL1
SH3GL2
SH3GL3
SH3GLB1
SNAP25
SNX9
SRC
SUMO1
TIMM50
UBE2I
Entrez ID
29763
1759
HPRD ID
05937
03851
Ensembl ID
ENSG00000165912
ENSG00000106976
Uniprot IDs
Q9UKS6
Q05193
PDB IDs
1DYN
2DYN
2X2E
2X2F
3SNH
3ZYC
3ZYS
Enriched GO Terms of Interacting Partners
?
Cell Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Cell Projection Organization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Guidance
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Development
Regulation Of Ras Protein Signal Transduction
Anatomical Structure Development
Cell Differentiation
Generation Of Neurons
Regulation Of Small GTPase Mediated Signal Transduction
Neuron Differentiation
Neurogenesis
Developmental Process
Regulation Of Ras GTPase Activity
Synaptic Vesicle Endocytosis
Cell Development
Synaptic Vesicle Recycling
Establishment Of Organelle Localization
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Endocytosis
Organelle Localization
Establishment Of Vesicle Localization
Nervous System Development
Regulation Of GTPase Activity
Vesicle Localization
Neurotrophin TRK Receptor Signaling Pathway
Signaling
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Catalytic Activity
Locomotion
Regulation Of Signaling
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cell Communication
Cell Surface Receptor Signaling Pathway
Endocytosis
Vesicle-mediated Transport
Regulation Of Cellular Component Organization
Positive Regulation Of Protein Complex Assembly
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cell Morphogenesis
Cellular Component Assembly
Neuron Projection Morphogenesis
Positive Regulation Of Cellular Component Biogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Membrane Organization
Transport
Axon Guidance
Cell Projection Organization
Regulation Of Signaling
Neuron Projection Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Protein Complex Assembly
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Chemotaxis
Synaptic Vesicle Transport
Regulation Of Vesicle-mediated Transport
Regulation Of Endocytosis
Neuron Development
Generation Of Neurons
Membrane Tubulation
Signaling
Axonogenesis
Anatomical Structure Development
Protein Complex Assembly
Neurogenesis
Cell Communication
Anatomical Structure Morphogenesis
Locomotion
Neurotrophin TRK Receptor Signaling Pathway
Synaptic Vesicle Endocytosis
Cell Morphogenesis Involved In Differentiation
Axon Development
Enzyme Linked Receptor Protein Signaling Pathway
Synaptic Vesicle Recycling
Regulation Of Signal Transduction
Neurotrophin Signaling Pathway
Regulation Of Phosphorylation
Cell Morphogenesis Involved In Neuron Differentiation
Synaptic Transmission
Positive Regulation Of Metabolic Process
Neuron Differentiation
Negative Regulation Of Endocytosis
Tagcloud
?
a432t
a452v
ankk1
arrb2
cdh13
chrna2
chrna9
dbh
drd2
eas
fagerstrom
gabbr2
grin3a
mstcc
n549s
nrxn1
nrxn2
nrxn3
ntrk2
r480h
rs139982841
rs142807401
rs34755188
rs75981117
skat
tas2r38
v132l
v389l
wss
Tagcloud (Difference)
?
a432t
a452v
ankk1
arrb2
cdh13
chrna2
chrna9
dbh
drd2
eas
fagerstrom
gabbr2
grin3a
mstcc
n549s
nrxn1
nrxn2
nrxn3
ntrk2
r480h
rs139982841
rs142807401
rs34755188
rs75981117
skat
tas2r38
v132l
v389l
wss
Tagcloud (Intersection)
?