TERF2IP and TBCA

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		TERF2IP	TBCA
Gene Name		telomeric repeat binding factor 2, interacting protein	tubulin folding cofactor A
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mre11 Complex	Nucleolus Cytoplasm Microtubule Microtubule Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Telomeric DNA Binding	Poly(A) RNA Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Telomere Maintenance Transcription, DNA-templated Regulation Of Transcription, DNA-templated Telomere Maintenance Via Telomerase Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance Via Telomere Lengthening Protection From Non-homologous End Joining At Telomere Negative Regulation Of Telomere Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Chromosome, Telomeric Region	Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Protein folding Post-chaperonin tubulin folding pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		125 interactors: ADA AIMP2 AK1 AKR1A1 AKR1B10 AKR7A3 AKT1 ANXA5 AP2B1 APEX1 ARPP21 BABAM1 BANP BCL7B C1orf174 C9orf78 CALML3 CHMP2B COTL1 CPNE2 CPNE3 CRK CRYBB1 CRYGS CTBP1 DBNL DDX23 DDX24 DDX39A DHX38 DNMT3A DPP3 ENAH EPAS1 EPS8L1 FABP2 FAM122A GAGE5 GAMT GNMT GPKOW HAAO HAGH HDGFRP3 HIST1H1A HIST1H2AL HIST1H4B HMGB1 HMGB3 HMGN3 HMGN4 HNRNPK IDO1 IL1RN LANCL2 LGALSL MAGOHB MCM2 MDH1 MPG MRTO4 MT1X MT3 NAIF1 NASP NOL3 NUDT14 NUDT18 NUMA1 NXNL1 OCM2 OGFR PACSIN2 PACSIN3 PAFAH1B3 PCNP PCP4 PEA15 PGLS PGM1 PML PNMT POLD1 PPM1G PPP1R2 PPP6R3 PRDX6 PRX PTMA RABIF RAD50 RASSF5 RBBP9 RECQL4 RGMA RIF1 RPAP1 RPP25 S100P SBDS SCLY SCRN2 SET SMARCC2 SNCG SP100 TALDO1 TBC1D10A TBCA TERF2 TMSB10 TMSB4Y TOR1AIP1 TSSC4 TWF2 UCHL1 VGLL4 WDR5 WIPI2 XAGE2 XPO1 XRCC5 XRCC6 ZNF146 ZNF414	2 interactors: TAF9 TERF2IP
Entrez ID		54386	6902
HPRD ID		05452	18166
Ensembl ID		ENSG00000166848	ENSG00000171530
Uniprot IDs		Q9NYB0	B4DT30 E5RHG6 O75347 Q6FGD7
PDB IDs		1FEX 3K6G	1H7C
Enriched GO Terms of Interacting Partners?		Chromosome Organization Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Organelle Organization Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process DNA Conformation Change Chromatin Modification Cell Cycle Cellular Response To Stress DNA Metabolic Process Cellular Response To DNA Damage Stimulus Sequestering Of Actin Monomers DNA Recombination Telomere Maintenance Via Telomere Lengthening Catabolic Process DNA Duplex Unwinding Cellular Aldehyde Metabolic Process Cellular Hyperosmotic Salinity Response DNA Geometric Change DNA Replication Energy Reserve Metabolic Process Nucleosome Organization Organophosphate Catabolic Process Response To Stress Chromatin Assembly Or Disassembly Deoxyribose Phosphate Catabolic Process Cellular Localization Cellular Metabolic Process Protein Localization To Nucleus Glycogen Metabolic Process Nucleocytoplasmic Transport Chromatin Remodeling Base-excision Repair Cellular Response To X-ray Nuclear Transport Aromatic Compound Catabolic Process Nucleosome Assembly Deoxyribonucleotide Catabolic Process DNA Strand Elongation Involved In DNA Replication Small Molecule Metabolic Process DNA Strand Elongation Biosynthetic Process Chromatin Assembly Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Transport Energy Derivation By Oxidation Of Organic Compounds	Regulation Of Response To DNA Damage Stimulus Negative Regulation Of DNA Recombination At Telomere Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To DNA Damage Stimulus Regulation Of Telomere Maintenance Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator RNA-dependent DNA Replication Chromosome Organization Negative Regulation Of DNA Recombination Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Double-strand Break Repair Protein Localization To Chromosome Positive Regulation Of Response To Cytokine Stimulus Telomere Maintenance Via Telomere Lengthening Regulation Of Signal Transduction By P53 Class Mediator Histone H3 Acetylation Cellular Response To Stress Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Repair Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of DNA Recombination Negative Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Regulation Of Cellular Component Organization DNA-templated Transcription, Elongation Response To Interleukin-1 Negative Regulation Of Chromosome Organization Protein Stabilization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription, DNA-templated Histone Acetylation Negative Regulation Of Protein Catabolic Process Positive Regulation Of Cell Growth Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation RNA Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Internal Protein Amino Acid Acetylation
Tagcloud ?		acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 tinf tinf2 yates	ac aggregates brains chief cilostazol ck2 ck2alpha concomitantly deposits elusive endogenously gsk3beta hallmarks hyperphosphorylated kt5720 mum n2a n2aswe neurodegeneration overproduced pka resveratrol sirt1 sirtinol suppress suppresses swedish tau tyr216
Tagcloud (Difference) ?		acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 tinf tinf2 yates	ac aggregates brains chief cilostazol ck2 ck2alpha concomitantly deposits elusive endogenously gsk3beta hallmarks hyperphosphorylated kt5720 mum n2a n2aswe neurodegeneration overproduced pka resveratrol sirt1 sirtinol suppress suppresses swedish tau tyr216
Tagcloud (Intersection) ?