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TERF2IP and CPNE3
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TERF2IP
CPNE3
Description
TERF2 interacting protein
copine 3
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Nuclear Body
Shelterin Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Cell Junction
Azurophil Granule Membrane
Extracellular Exosome
Anchoring Junction
Molecular Function
Protein Binding
Phosphatase Binding
Telomeric DNA Binding
G-rich Strand Telomeric DNA Binding
RNA Binding
Protein Serine/threonine Kinase Activity
Protein Binding
Calcium-dependent Phospholipid Binding
Receptor Tyrosine Kinase Binding
Metal Ion Binding
Calcium-dependent Protein Binding
Biological Process
Telomere Maintenance
Negative Regulation Of Protein Phosphorylation
Regulation Of DNA-templated Transcription
Telomere Maintenance Via Telomerase
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Telomere Capping
Protection From Non-homologous End Joining At Telomere
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Telomere Maintenance
Intracellular Signal Transduction
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Chromosome, Telomeric Region
Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Cell Migration
ERBB2 Signaling Pathway
Cellular Response To Calcium Ion
Cellular Response To Growth Factor Stimulus
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Glycerophospholipid biosynthesis
Neutrophil degranulation
Drugs
Diseases
GWAS
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Smoking status (ever vs never smokers) (
30643258
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Weight (
34074324
)
Intelligence (MTAG) (
29326435
)
Interacting Genes
122 interacting genes:
ADA
AIMP2
AK1
AKR1A1
AKR1B10
AKR7A3
AKT1
ANXA5
ANXA8L1
AP2B1
APEX1
ARPP21
BABAM1
BANP
BCL7B
C1orf174
CALML3
CHMP2B
COTL1
CPNE2
CPNE3
CRK
CRYBB1
CRYGS
CTBP1
DBNL
DDX23
DDX24
DDX39A
DNMT3A
DPP3
ENAH
EPAS1
EPS8L1
ETS2
FABP2
GAGE5
GAMT
GNMT
H1-1
H2AC16
H4C2
HAAO
HAGH
HDGFL3
HMGB1
HMGB3
HMGN3
HMGN4
HNRNPK
IDO1
IL1RN
LANCL2
LGALSL
MAGOHB
MCM2
MDH1
MPG
MRTO4
MT1X
MT3
NAIF1
NASP
NOL3
NPSR1
NUDT14
NUDT18
NXNL1
OCM2
OGFR
PABIR1
PACSIN2
PACSIN3
PAFAH1B3
PCNP
PCP4
PEA15
PGLS
PGM1
PIAS1
PML
PNMT
PPP1R2
PPP6R3
PRDX6
PRX
PTEN
PTMA
RABIF
RAD50
RASSF5
RBBP9
RECQL4
RGMA
RIF1
RPAP1
RPP25
S100P
SBDS
SCLY
SCRN2
SET
SNCG
SP100
TALDO1
TBC1D10A
TBCA
TERF2
TMSB10
TMSB4Y
TOR1AIP1
TSSC4
TWF2
UCHL1
VGLL4
WDR5
WIPI2
XAGE2
XPO1
XRCC5
ZNF146
ZNF414
8 interacting genes:
LINC00624
POT1
QARS1
RHOU
SNCA
TERF1
TERF2IP
TINF2
Entrez ID
54386
8895
HPRD ID
05452
05016
Ensembl ID
ENSG00000166848
ENSG00000085719
Uniprot IDs
Q9NYB0
O75131
PDB IDs
1FEX
3K6G
4RQI
7OZ0
8RD4
Enriched GO Terms of Interacting Partners
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Cytoplasm
Protein Binding
Cytosol
Double-stranded Telomeric DNA Binding
Nucleobase-containing Compound Metabolic Process
Chromatin Organization
Chromosome, Telomeric Region
Telomere Organization
Chromatin Remodeling
Protein Domain Specific Binding
Nucleus
Telomere Maintenance
Nucleoplasm
Energy Reserve Metabolic Process
Chromosome Organization
Glycogen Metabolic Process
Alcohol Dehydrogenase (NADP+) Activity
Cellular Detoxification Of Aldehyde
Extracellular Exosome
Telomere Maintenance In Response To DNA Damage
Myelin Maintenance
Negative Regulation Of T-circle Formation
Polysaccharide Metabolic Process
Nucleic Acid Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Maintenance Of Protein Localization In Organelle
DNA Metabolic Process
Plasma Membrane Organization
Quinolinate Biosynthetic Process
Allyl-alcohol Dehydrogenase Activity
DNA Recombination
Helicase Activity
Regulation Of Growth
Generation Of Precursor Metabolites And Energy
Calcium-dependent Phospholipid Binding
Negative Regulation Of DNA Metabolic Process
Cadherin Binding
Regulation Of Cellular Response To Stress
Quinolinate Metabolic Process
Mre11 Complex
Negative Regulation Of Cellular Component Organization
Carbohydrate Metabolic Process
Regulation Of Cell Growth
Actin Monomer Binding
Positive Regulation Of Proteolysis
Maintenance Of Protein Location In Cell
RNA-templated DNA Biosynthetic Process
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance
G-rich Strand Telomeric DNA Binding
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Chromosome Organization
Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Chromosome Organization
Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
RNA-templated DNA Biosynthetic Process
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Organelle Organization
Telomere Assembly
Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Cellular Component Organization
Regulation Of Chromosome Organization
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Cellular Component Organization
Regulation Of DNA Biosynthetic Process
Telomeric D-loop Disassembly
DNA Biosynthetic Process
Chromosome Organization
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of Organelle Organization
Chromosome
Protein Kinase Inhibitor Activity
Regulation Of Cellular Component Organization
DNA Metabolic Process
Organelle Organization
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Response To Desipramine
Negative Regulation Of Norepinephrine Uptake
Phospholipase D Inhibitor Activity
Positive Regulation Of SNARE Complex Assembly
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Establishment Of Protein Localization To Telomere
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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