DISC1 and ITSN1

  • Number of citations of the paper that reports this interaction (PubMedID 12812986)
  • 80
  • Data Source:
  • HPRD (two hybrid)

DISC1

ITSN1

Description disrupted in schizophrenia 1 intersectin 1 (SH3 domain protein)
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
Interacting Genes 113 interacting genes: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365 82 interacting genes: AGFG1 AGFG2 AP2B1 ARF6 ARFIP2 ARHGAP31 ASAP2 CCNO CDC42 CEP85L CLIP2 CLTC CSNK2B CYTH1 DAB2 DES DISC1 DLGAP1 DNM1 DNM2 EEF1A1 EPHB2 EPN2 EPS15 EPS15L1 FCHSD2 FNBP1 FNBP4 GAREML GCC1 GOLGA5 HIP1 HRAS ITSN2 KHDRBS1 KIF16B KIF5A LMO4 MAPK6 MAPK8IP2 MRPL20 MTUS2 PACSIN3 PDCD6IP PFDN5 PICALM PIK3AP1 PIK3C2B PIK3R1 PLK1 PPFIA2 PPL PREX1 RAB11FIP2 RAB5A RABEP1 RAI14 RNF40 RPS6KA5 SCAMP1 SCOC SF3B4 SH3GL2 SMARCC2 SNAP23 SNAP25 SNX5 SOS1 SPDL1 SPRY2 STON2 SYNJ1 SYNJ2 TK1 TRIM8 TSG101 UBE2K UNC119 WASL WBP11 ZAK ZFPM2
Entrez ID 27185 6453
HPRD ID 05553 03898
Ensembl ID ENSG00000162946 ENSG00000205726
Uniprot IDs C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5 A7XZY7 F8W7U0 Q15811 Q6PD56
PDB IDs 1KI1 2KGR 2KHN 3FIA 3QBV 4IIM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
cbr1  david  degs  downloaded  dyrk1a  egr1  encyclopedia  geo  gse  hmgn1  hypergeometric  interrogate  kegg  kyoto  macromolecular  multiarray  mycmax  mzf1  nfe2  nfy  olf1  ominibus  pax5  rma  rp58  son  srebp1  tmem50b  ttc3 
Tagcloud (Difference) ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
cbr1  david  degs  downloaded  dyrk1a  egr1  encyclopedia  geo  gse  hmgn1  hypergeometric  interrogate  kegg  kyoto  macromolecular  multiarray  mycmax  mzf1  nfe2  nfy  olf1  ominibus  pax5  rma  rp58  son  srebp1  tmem50b  ttc3 
Tagcloud (Intersection) ?