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ITSN1 and PFDN5
Number of citations of the paper that reports this interaction (PubMedID
18654987
)
0
Data Source:
BioGRID
(two hybrid)
ITSN1
PFDN5
Description
intersectin 1
prefoldin subunit 5
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Cytoplasm
Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Endomembrane System
Membrane
Lamellipodium
Cytoplasmic Vesicle
Presynaptic Membrane
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Recycling Endosome
Apical Dendrite
Intracellular Vesicle
Postsynaptic Endocytic Zone
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
Nucleus
Cytoplasm
Cytosol
Prefoldin Complex
Protein-containing Complex
Intermediate Filament Cytoskeleton
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Molecular Adaptor Activity
Proline-rich Region Binding
Amyloid-beta Binding
Transcription Corepressor Activity
Protein Binding
Unfolded Protein Binding
Biological Process
Exocytosis
Endocytosis
Intracellular Protein Localization
Regulation Of Cell Communication
Protein Transport
Endosomal Transport
Regulation Of Signaling
Intracellular Signal Transduction
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Growth Hormone Secretion
Positive Regulation Of Dendritic Spine Development
Regulation Of Postsynapse Organization
Clathrin-dependent Synaptic Vesicle Endocytosis
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Caveolin-mediated Endocytosis
Regulation Of DNA-templated Transcription
Protein Folding
Negative Regulation Of DNA-templated Transcription
Retina Development In Camera-type Eye
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Amyloid Fibril Formation
RNA Polymerase I Assembly
RNA Polymerase II Core Complex Assembly
RNA Polymerase III Assembly
Pathways
NRAGE signals death through JNK
EPHB-mediated forward signaling
EPHB-mediated forward signaling
G alpha (12/13) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
CDC42 GTPase cycle
RHOQ GTPase cycle
RHOG GTPase cycle
Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Bitter non-alcoholic beverage consumption (
31046077
)
Educational attainment (
25201988
)
Height (
31562340
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
QT interval (
29213071
)
Red blood cell count (
32888494
)
Red cell distribution width (
27863252
32888494
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
140 interacting genes:
AGFG1
AGFG2
AJUBA
ANKRD36
ANKRD54
ARF6
ARFIP2
ARHGAP31
ASAP2
BECN1
BFSP1
BRCC3
BRWD3
CCDC24
CCNO
CDC42
CEP85L
CLIP2
CLTC
COG4
CSNK2B
CYTH1
CYTH3
DAB1
DAB2
DES
DISC1
DLGAP1
DNAI7
DNAJA2
DNM1
DNM2
DST
DYNC1H1
EEF1A1
EPHB2
EPN2
EPS15
EXOC1
FCHO1
FCHO2
FCHSD2
FNBP1
FNBP4
GAREM2
GCC1
GFAP
GNPTG
GOLGA5
HIP1
HNRNPK
HRAS
IFT74
ITSN2
KHDRBS1
KIF16B
KIF5A
KIF5C
KRT222
LMO3
LMO4
MAP3K20
MAPK6
MAPK8IP2
MED4
MRPL20
MTUS2
MYH14
NASP
NEFL
NEFM
NEMF
PACSIN3
PDCD6IP
PDE2A
PDZD8
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
PRRG4
RAB11FIP2
RAB5A
RABEP1
RAI14
RALBP1
REPS1
REPS2
RIN1
RNF40
RPS6KA5
RRBP1
SCAI
SCAMP1
SCOC
SF3B4
SH3GL2
SHANK3
SIAH1
SMARCC2
SMC1A
SNAP23
SNAP25
SNRNP70
SNX5
SNX6
SOS1
SOS2
SPDL1
SPECC1
SPRY2
SPTAN1
SPTBN1
STON2
SYNC
SYNE1
SYNJ1
SYNJ2
TK1
TRAF3IP1
TRIM5
TRIM8
TRPM7
TSG101
TTC27
UBC
UBE2K
UNC119
VLDLR
WASL
WBP11
WHAMM
ZFC3H1
ZFPM2
ZMYM5
113 interacting genes:
ABI2
ANKRD55
ATOSB
BCAS2
BCL6
BHLHE40
BRMS1
C10orf55
C10orf62
C22orf39
CALCOCO2
CCDC198
CEBPA
CIMIP1
CSPP1
DMRT3
DOK4
DOK5
EEIG1
ELK3
ESPNL
FAAP20
FAM110A
FAM221A
FAM222B
FAM90A1
GLRX3
GLYCTK
GPANK1
GSTO2
GUCD1
HAPLN2
HHEX
HOXB9
HOXC8
IKBKG
IKZF3
IL16
INCA1
IRX2
IRX6
ITSN1
KCTD9
KDM1A
KLHL38
KLHL42
LARP4
LNX1
MAP2K5
METTL21A
MISP
MRPL45
MYC
MYOT
MYOZ1
NEUROG2
NOXA1
NTAQ1
PATZ1
PAX9
PFDN6
PHF1
PHF24
PILRA
PITX1
PITX2
POGZ
PRKAB2
PRPF18
PRR35
PSMB4
PSMB8
PSME3
RIBC1
RIPPLY1
RSRC2
RUSC1
SAXO1
SAXO4
SCNM1
SDCBP
SHISA6
SLAIN1
SMAP1
SMG9
SNAI1
SNRNP25
SNRPB
SOHLH1
SPAG8
SPG21
SPMIP2
SPMIP4
SYCE1L
SYT17
TAF6L
TBX3
TCF19
TFG
TLE5
TP73
TRAPPC6A
TRIM28
TUBA1B
TUBA3C
VAX2
VEZF1
VGLL1
WDR25
WHR1
YPEL5
ZC2HC1C
ZNF148
Entrez ID
6453
5204
HPRD ID
03898
05359
Ensembl ID
ENSG00000205726
ENSG00000123349
Uniprot IDs
A7XZY7
F8W7U0
Q15811
Q6PD56
Q99471
PDB IDs
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
5HZI
5HZJ
5HZK
6GBU
6H5T
6NR8
6NR9
6NRB
6NRC
6NRD
7WU7
Enriched GO Terms of Interacting Partners
?
Endocytosis
Vesicle-mediated Transport
Import Into Cell
Cytoplasm
Cytosol
Establishment Of Localization In Cell
Clathrin-coated Pit
Clathrin Coat Assembly
Cytoskeleton Organization
Organelle Organization
Cytoskeleton
Regulation Of Cellular Component Organization
Receptor-mediated Endocytosis
Organelle Localization
Membrane Organization
Cellular Component Assembly
Clathrin-coated Vesicle
Protein Transport
Clathrin-dependent Endocytosis
Intermediate Filament-based Process
Cellular Localization
Establishment Of Organelle Localization
Intracellular Transport
Negative Regulation Of Cellular Component Organization
Synaptic Vesicle Endocytosis
Establishment Of Protein Localization
Regulation Of Protein Localization To Cell Periphery
Presynaptic Endocytosis
Vesicle-mediated Transport In Synapse
Intermediate Filament Cytoskeleton Organization
Intracellular Protein Localization
Protein-containing Complex Assembly
Clathrin Coat Of Coated Pit
Intermediate Filament Cytoskeleton
Protein-containing Complex Organization
Structural Constituent Of Cytoskeleton
Post-Golgi Vesicle-mediated Transport
Glutamatergic Synapse
Microtubule Binding
Establishment Of Vesicle Localization
Endosomal Transport
Cell Cortex
Cytoplasmic Vesicle
Golgi Vesicle Transport
Regulation Of Protein Localization To Plasma Membrane
Vesicle Localization
Cytoskeleton-dependent Intracellular Transport
Cell Projection Organization
Mitotic Cytokinesis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Chromatin
Negative Regulation Of RNA Metabolic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Sequence-specific Double-stranded DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Binding
Positive Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of RNA Metabolic Process
Pattern Specification Process
MRF Binding
Regionalization
Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
E-box Binding
Axonemal A Tubule Inner Sheath
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Tagcloud (Intersection)
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