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ITSN1 and SCOC
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
ITSN1
SCOC
Gene Name
intersectin 1 (SH3 domain protein)
short coiled-coil protein
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Plasma Membrane
Coated Pit
Lamellipodium
Cell Junction
Endocytic Vesicle
Neuron Projection
Synapse
Golgi Membrane
Endosome
Trans-Golgi Network
Cytosol
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Kinase Activator Activity
Protein Complex Scaffold
Proline-rich Region Binding
Protein Binding
Biological Process
Small GTPase Mediated Signal Transduction
Axon Guidance
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Synaptic Vesicle Endocytosis
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Positive Regulation Of Macroautophagy
Pathways
Signaling by GPCR
Signalling by NGF
Axon guidance
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
Rho GTPase cycle
EPHB-mediated forward signaling
GPCR downstream signaling
NRAGE signals death through JNK
Signaling by Rho GTPases
EPH-Ephrin signaling
G alpha (12/13) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions
82 interactors:
AGFG1
AGFG2
AP2B1
ARF6
ARFIP2
ARHGAP31
ASAP2
CCNO
CDC42
CEP85L
CLIP2
CLTC
CSNK2B
CYTH1
DAB2
DES
DISC1
DLGAP1
DNM1
DNM2
EEF1A1
EPHB2
EPN2
EPS15
EPS15L1
FCHSD2
FNBP1
FNBP4
GAREML
GCC1
GOLGA5
HIP1
HRAS
ITSN2
KHDRBS1
KIF16B
KIF5A
LMO4
MAPK6
MAPK8IP2
MRPL20
MTUS2
PACSIN3
PDCD6IP
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
RAB11FIP2
RAB5A
RABEP1
RAI14
RNF40
RPS6KA5
SCAMP1
SCOC
SF3B4
SH3GL2
SMARCC2
SNAP23
SNAP25
SNX5
SOS1
SPDL1
SPRY2
STON2
SYNJ1
SYNJ2
TK1
TRIM8
TSG101
UBE2K
UNC119
WASL
WBP11
ZAK
ZFPM2
8 interactors:
ARL1
FEZ1
FEZ2
ITSN1
KRT40
MAPK8
SCHIP1
TCF4
Entrez ID
6453
60592
HPRD ID
03898
18027
Ensembl ID
ENSG00000205726
ENSG00000153130
Uniprot IDs
A7XZY7
F8W7U0
Q15811
Q6PD56
Q9UIL1
PDB IDs
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
4BWD
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Endocytosis
Vesicle Organization
Cellular Localization
Establishment Of Localization In Cell
Regulation Of Vesicle-mediated Transport
Signaling
Synaptic Transmission
Regulation Of Cellular Component Organization
Establishment Of Organelle Localization
Cell Communication
Regulation Of Signaling
Organelle Organization
Protein Localization
Cell Differentiation
Synaptic Vesicle Transport
Cell-cell Signaling
Membrane Budding
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Organelle Localization
Regulation Of ERBB Signaling Pathway
Positive Regulation Of Metabolic Process
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Morphogenesis
Negative Regulation Of ERBB Signaling Pathway
Post-Golgi Vesicle-mediated Transport
Establishment Of Vesicle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Vesicle Localization
Transport
Cell Morphogenesis Involved In Neuron Differentiation
Axon Guidance
Generation Of Neurons
Cell Morphogenesis Involved In Differentiation
Membrane Organization
Cell Projection Morphogenesis
Cell Part Morphogenesis
Establishment Of Protein Localization
Cell Projection Organization
Synaptic Vesicle Recycling
Axonogenesis
Cellular Protein Complex Assembly
Neurogenesis
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Intracellular Transport
Cell Morphogenesis
Response To External Stimulus
Axon Guidance
Organelle Localization
Positive Regulation Of Protein Kinase B Signaling
Axonogenesis
Axon Development
Cellular Response To Growth Factor Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Response To Growth Factor
Chemotaxis
Generation Of Neurons
Regulation Of Protein Kinase B Signaling
Positive Regulation Of Cell Death
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Neuron Projection Morphogenesis
Neurogenesis
Regulation Of Protein Binding
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Cell Morphogenesis Involved In Differentiation
Cell Development
Maintenance Of DNA Repeat Elements
Neuron Projection Development
JUN Phosphorylation
Cell Projection Morphogenesis
Establishment Of Localization In Cell
Cell Part Morphogenesis
Vesicle Localization
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Deacetylase Activity
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Apoptotic Process
Neurotrophin Signaling Pathway
Negative Regulation Of Programmed Cell Death
Embryonic Genitalia Morphogenesis
Neuron Development
Positive Regulation Of Intracellular Transport
Negative Regulation Of Cell Death
Positive Regulation Of Determination Of Dorsal Identity
Myoblast Fate Commitment
Nervous System Development
Regulation Of Binding
Cellular Response To Stimulus
Positive Regulation Of Hydrolase Activity
Secretory Granule Localization
Cell Morphogenesis
Ossification
Tagcloud
?
cbr1
david
degs
downloaded
dyrk1a
egr1
encyclopedia
geo
gse
hmgn1
hypergeometric
interrogate
kegg
kyoto
macromolecular
multiarray
mycmax
mzf1
nfe2
nfy
olf1
ominibus
pax5
rma
rp58
son
srebp1
tmem50b
ttc3
Tagcloud (Difference)
?
cbr1
david
degs
downloaded
dyrk1a
egr1
encyclopedia
geo
gse
hmgn1
hypergeometric
interrogate
kegg
kyoto
macromolecular
multiarray
mycmax
mzf1
nfe2
nfy
olf1
ominibus
pax5
rma
rp58
son
srebp1
tmem50b
ttc3
Tagcloud (Intersection)
?