DISC1 and ACTN2

  • Number of citations of the paper that reports this interaction (PubMedID 12812986)
  • 80
  • Data Source:
  • HPRD (two hybrid, in vivo)

DISC1

ACTN2

Description disrupted in schizophrenia 1 actinin, alpha 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
Interacting Genes 113 interacting genes: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365 59 interacting genes: ACTN3 ADAM12 ADORA2A ANG ATXN2 ATXN7 BRMS1L CAMK2A CAMK2D CAMK2G CAPN1 COIL DISC1 DLG1 DLG4 EPS8L1 ERBB2IP FAM154A FBXL22 GRIN1 GRIN2B ITGB3BP KAT2B KCNA4 KCNA5 KCNN2 LDB3 LRP12 LRRC7 MED14 MICALL2 MOS MYOZ1 MYOZ2 MYOZ3 MYPN NCOA2 NCOR1 NOS3 NR1I2 NRIP1 PALLD PDLIM1 PDLIM3 PKD2 RAVER1 RPL35 RTP5 SELE SNAI1 SNW1 SP100 SSX2IP ST7 SYNPO2 TNN TTN UTRN ZNF446
Entrez ID 27185 88
HPRD ID 05553 00019
Ensembl ID ENSG00000162946 ENSG00000077522
Uniprot IDs C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5 B2RCS5 P35609 Q59FD9
PDB IDs 1H8B 1HCI 1QUU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
actinin  barr  cd99  cdk8  dnajb2  e2f  e2f2  ebv  epstein  fatigue  hsp40  hybridized  indicative  infectious  infective  irritability  isg20  malaise  microarrays  mononucleosis  oligonucleotides  pbmc  persist  pilot  recovered  resolve  somnolence  spotted  uneventfully 
Tagcloud (Difference) ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
actinin  barr  cd99  cdk8  dnajb2  e2f  e2f2  ebv  epstein  fatigue  hsp40  hybridized  indicative  infectious  infective  irritability  isg20  malaise  microarrays  mononucleosis  oligonucleotides  pbmc  persist  pilot  recovered  resolve  somnolence  spotted  uneventfully 
Tagcloud (Intersection) ?