DISC1 and EXOC1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		DISC1	EXOC1
Gene Name		disrupted in schizophrenia 1	exocyst complex component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Centrosome Microtubule Postsynaptic Density Cell Junction Ciliary Basal Body Postsynaptic Membrane	Exocyst Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Positive Regulation Of Neuroblast Proliferation Regulation Of Neuron Projection Development Cerebral Cortex Radially Oriented Cell Migration Cell Proliferation In Forebrain Positive Regulation Of Wnt Signaling Pathway TOR Signaling Cellular Protein Localization Mitochondrial Calcium Ion Homeostasis Canonical Wnt Signaling Pathway Regulation Of Synapse Maturation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Alzheimer's disease ( 19118814) Amyotrophic lateral sclerosis ( 19451621) Neuranatomic and neurocognitive phenotypes ( 21483430) Response to antineoplastic agents ( 21659360) Response to statin therapy ( 20339536)	Cervical cancer ( 23817570)
Protein-Protein Interactions		113 interactors: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365	28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		27185	55763
HPRD ID		05553	07615
Ensembl ID		ENSG00000162946	ENSG00000090989
Uniprot IDs		C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5	Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Movement Of Cell Or Subcellular Component Cellular Localization Microtubule-based Process Nervous System Development Establishment Of Localization In Cell Neurogenesis G2/M Transition Of Mitotic Cell Cycle Generation Of Neurons Microtubule Cytoskeleton Organization Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Process Cellular Component Assembly Cell Projection Organization Mitotic Cell Cycle Microtubule-based Transport Cell Cycle Process Organelle Localization Cytoskeleton Organization Cell Cycle Cell Projection Morphogenesis Cell Part Morphogenesis Anatomical Structure Development System Development Membrane Organization Cell Differentiation Cell Morphogenesis Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Organelle Transport Along Microtubule Developmental Process Protein Localization Microtubule-based Movement Axonogenesis Mitotic Nuclear Division Locomotion Establishment Of Organelle Localization Axon Guidance Vesicle Localization Axon Development Neuron Development Cellular Process Regulation Of Cellular Component Organization Multicellular Organismal Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Neurogenesis Cell Projection Assembly Neuron Differentiation Intracellular Transport Spindle Organization	Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport
Tagcloud ?		accelerate aggregated allosteric amplify appropriated assemblies assembly biochemically capsid catalytically collections commonality conceptualized continuum crowded exploit governed labile machines multimers multiprotein pathologically prions replicating replicative reprogrammed reset suited transmissibility
Tagcloud (Difference) ?		accelerate aggregated allosteric amplify appropriated assemblies assembly biochemically capsid catalytically collections commonality conceptualized continuum crowded exploit governed labile machines multimers multiprotein pathologically prions replicating replicative reprogrammed reset suited transmissibility
Tagcloud (Intersection) ?