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LCE4A and OTX1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LCE4A
OTX1
Gene Name
late cornified envelope 4A
orthodenticle homeobox 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Biological Process
Keratinization
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
23 interactors:
ADAMTSL4
HOXA1
KRT31
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
MDFI
MEOX2
OTX1
PLSCR1
RGS17
RGS20
RNF111
SMCP
SPRY2
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
Entrez ID
199834
5013
HPRD ID
17264
08964
Ensembl ID
ENSG00000187170
ENSG00000115507
Uniprot IDs
Q5TA78
P32242
PDB IDs
Enriched GO Terms of Interacting Partners
?
Pattern Specification Process
Positive Regulation Of Metabolic Process
Embryonic Organ Morphogenesis
Inner Ear Morphogenesis
Ear Morphogenesis
Positive Regulation Of Gene Expression
Embryonic Organ Development
Inner Ear Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Embryo Development
Ear Development
Embryonic Morphogenesis
Anterior/posterior Pattern Specification
Positive Regulation Of Transcription, DNA-templated
Termination Of G-protein Coupled Receptor Signaling Pathway
Optokinetic Behavior
Abducens Nerve Formation
Termination Of Signal Transduction
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Catalytic Activity
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Facial Nucleus Development
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Morphogenesis
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Rhombomere 4 Development
Semicircular Canal Formation
Regulation Of Signal Transduction
Embryonic Skeletal System Morphogenesis
Negative Regulation Of Signal Transduction
Epithelium Development
Rhombomere 3 Development
Rhombomere 5 Development
Metencephalon Development
Negative Regulation Of Signaling
Developmental Process
Ubiquitin-dependent SMAD Protein Catabolic Process
Somite Specification
Phosphatidylserine Biosynthetic Process
Sensory Perception Of Sound
Regulation Of Signaling
Embryonic Skeletal System Development
Sensory Organ Development
Diencephalon Morphogenesis
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Hindbrain Development
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?