Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
OTX1 and CHIC2
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
OTX1
CHIC2
Gene Name
orthodenticle homeobox 1
cysteine-rich hydrophobic domain 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cellular_component
Golgi-associated Vesicle
Plasma Membrane
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Molecular_function
Protein Binding
Biological Process
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Golgi To Plasma Membrane Transport
Biological_process
Pathways
Drugs
Diseases
GWAS
Blood pressure (
21909110
)
Protein-Protein Interactions
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
26 interactors:
CATSPER1
CDR2
CEP44
GMCL1
HOXA1
ITSN2
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
MDFI
MEOX2
NOTCH2NL
OTX1
PLEKHF2
PNMA1
SPERT
TCF4
TOP3B
TUBGCP4
U2AF2
Entrez ID
5013
26511
HPRD ID
08964
10373
Ensembl ID
ENSG00000115507
ENSG00000109220
Uniprot IDs
P32242
Q9UKJ5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Embryonic Organ Morphogenesis
Pattern Specification Process
Embryonic Organ Development
Anterior/posterior Pattern Specification
Embryo Development
Embryonic Morphogenesis
Optokinetic Behavior
Abducens Nerve Formation
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Facial Nucleus Development
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Diencephalon Development
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Inner Ear Morphogenesis
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Rhombomere 4 Development
Semicircular Canal Formation
Developmental Process
Rhombomere 3 Development
Rhombomere 5 Development
Maintenance Of DNA Repeat Elements
Positive Regulation Of Metabolic Process
Embryonic Skeletal System Morphogenesis
Ear Morphogenesis
Organ Morphogenesis
Metencephalon Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Somite Specification
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Blood Vessel Development
Multicellular Organismal Development
Regulation Of Transcription From RNA Polymerase II Promoter
Vasculature Development
Diencephalon Morphogenesis
Embryonic Genitalia Morphogenesis
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Embryonic Skeletal System Development
Myoblast Fate Commitment
Hindbrain Development
Single Organism Reproductive Process
Embryonic Neurocranium Morphogenesis
Secretory Granule Localization
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?