OTX1 and KRTAP10-8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		OTX1	KRTAP10-8
Gene Name		orthodenticle homeobox 1	keratin associated protein 10-8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Keratin Filament
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: CHIC2 CHRD COMP GEMIN8P4 GRN KCNK16 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4	163 interactors: ACY3 ADAMTSL3 ADAMTSL4 AEN AES ALDH3B1 ALPI APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 C19orf66 C9orf9 CARHSP1 CARKD CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LOC153684 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MTA1 MXI1 NAB2 NOTCH2NL NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR PVRL3 QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21
Entrez ID		5013	386681
HPRD ID		08964	11194
Ensembl ID		ENSG00000115507	ENSG00000187766
Uniprot IDs		P32242	P60410
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Keratinocyte Differentiation Epithelium Development Epidermis Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Tissue Development Epidermal Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Skin Development Organ Development Developmental Process Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Development Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Developmental Growth Involved In Morphogenesis Negative Regulation Of Signaling Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Multicellular Organismal Development Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway System Development Spindle Localization BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Epithelial Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Organ Morphogenesis Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Developmental Growth Regulation Of MAP Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Growth Regulation Of GTPase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity	Keratinization RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Pattern Specification Process Keratinocyte Differentiation Organ Development Epithelium Development Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Epidermis Development Tissue Development Negative Regulation Of Glomerulus Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Epidermal Cell Differentiation Macromolecule Biosynthetic Process Metanephric Mesenchyme Development Heterocycle Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Sperm Motility Negative Regulation Of Cell Proliferation Involved In Kidney Development Fertilization Biosynthetic Process Anterior/posterior Pattern Specification Anatomical Structure Development Epithelial Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Metanephric S-shaped Body Morphogenesis Single Fertilization System Development Branching Morphogenesis Of An Epithelial Tube Regulation Of Glomerular Mesangial Cell Proliferation Penetration Of Zona Pellucida S-shaped Body Morphogenesis Positive Regulation Of Immune Response To Tumor Cell Floor Plate Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Skin Development Bud Elongation Involved In Lung Branching Morphogenesis Of A Branching Epithelium Negative Regulation Of Mesenchymal Cell Apoptotic Process Epithelial Tube Branching Involved In Lung Morphogenesis Morphogenesis Of A Branching Structure
Tagcloud ?		17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Difference) ?		17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Intersection) ?