LCE4A and RGS17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE4A	RGS17
Gene Name		late cornified envelope 4A	regulator of G-protein signaling 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane
	Molecular Function		GTPase Activator Activity
	Biological Process	Keratinization	Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		23 interactors: ADAMTSL4 HOXA1 KRT31 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MEOX2 OTX1 PLSCR1 RGS17 RGS20 RNF111 SMCP SPRY2	18 interactors: ADRB2 AQP1 DHX37 GNAI1 GNAI3 HOXA1 LCE2A LCE3C LCE4A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SMCP TBC1D16
Entrez ID		199834	26575
HPRD ID		17264	06223
Ensembl ID		ENSG00000187170	ENSG00000091844
Uniprot IDs		Q5TA78	Q9UGC6
PDB IDs			1ZV4
Enriched GO Terms of Interacting Partners?		Pattern Specification Process Positive Regulation Of Metabolic Process Embryonic Organ Morphogenesis Inner Ear Morphogenesis Ear Morphogenesis Positive Regulation Of Gene Expression Embryonic Organ Development Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Embryo Development Ear Development Embryonic Morphogenesis Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Termination Of G-protein Coupled Receptor Signaling Pathway Optokinetic Behavior Abducens Nerve Formation Termination Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Facial Nucleus Development Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Semicircular Canal Formation Regulation Of Signal Transduction Embryonic Skeletal System Morphogenesis Negative Regulation Of Signal Transduction Epithelium Development Rhombomere 3 Development Rhombomere 5 Development Metencephalon Development Negative Regulation Of Signaling Developmental Process Ubiquitin-dependent SMAD Protein Catabolic Process Somite Specification Phosphatidylserine Biosynthetic Process Sensory Perception Of Sound Regulation Of Signaling Embryonic Skeletal System Development Sensory Organ Development Diencephalon Morphogenesis Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Hindbrain Development Regulation Of G-protein Coupled Receptor Protein Signaling Pathway	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Heat Generation Keratinocyte Differentiation Membrane Fusion Epidermal Cell Differentiation Temperature Homeostasis Bicarbonate Transport Vesicle Organization Skin Development Regulation Of Body Fluid Levels Vesicle Fusion Regulation Of Adenylate Cyclase Activity Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Epidermis Development Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Cyclase Activity Cellular Response To Retinoic Acid Organelle Fusion Facial Nucleus Development Carbon Dioxide Transmembrane Transport Corticotropin Secretion Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Establishment Or Maintenance Of Actin Cytoskeleton Polarity Developmental Process Regulation Of CAMP Biosynthetic Process DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Metanephric Proximal Convoluted Tubule Development Rhombomere 4 Development Nitric Oxide Transport Semicircular Canal Formation Cellular Response To Mercury Ion Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Renal System Process Regulation Of CAMP Metabolic Process Inner Ear Morphogenesis Membrane Organization Rhombomere 3 Development Rhombomere 5 Development Metanephric Proximal Tubule Development Fever Generation Organ Development Anatomical Structure Development
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