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OTX1 and RGS20
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
OTX1
RGS20
Gene Name
orthodenticle homeobox 1
regulator of G-protein signaling 20
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Cytoplasm
Plasma Membrane
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
GTPase Activator Activity
Protein Binding
Biological Process
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (z) signalling events
G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
33 interactors:
ADRB2
AQP1
CATSPER1
CRCT1
CREB5
FASLG
GLRX3
GNAI1
GNAI2
GNAI3
GNAO1
GNAZ
HOXA1
HSPD1
INS
KIF1A
KLHL38
KRTAP4-2
KRTAP5-6
KRTAP5-9
LCE1B
LCE2A
LCE2D
LCE3E
LCE4A
MAPKBP1
OSTM1
OTX1
PTGER3
PTPMT1
PVRL3
STMN2
TBC1D16
Entrez ID
5013
8601
HPRD ID
08964
06225
Ensembl ID
ENSG00000115507
ENSG00000147509
Uniprot IDs
P32242
H9NIM5
O76081
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Keratinization
Keratinocyte Differentiation
Epidermis Development
Developmental Process
Epidermal Cell Differentiation
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Organ Development
System Development
Multicellular Organismal Development
Anatomical Structure Development
Skin Development
Heat Generation
G-protein Coupled Receptor Signaling Pathway
Cell Differentiation
Regulation Of Adenylate Cyclase Activity
Regulation Of Cyclase Activity
Tissue Development
Regulation Of CAMP Biosynthetic Process
Epithelium Development
Regulation Of CAMP Metabolic Process
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Epithelial Cell Differentiation
Temperature Homeostasis
Membrane Fusion
Regulation Of Body Fluid Levels
Cell-cell Signaling
Negative Regulation Of CAMP Biosynthetic Process
Sensory Organ Development
Wound Healing
Bicarbonate Transport
Negative Regulation Of CAMP Metabolic Process
Eye Morphogenesis
Cell Activation
Negative Regulation Of Nucleotide Metabolic Process
Acute-phase Response
Regulation Of Catalytic Activity
Response To Wounding
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
B Cell Cytokine Production
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Isotype Switching To IgG Isotypes
Anion Homeostasis
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?