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OTX1 and KRTAP5-9
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
OTX1
KRTAP5-9
Gene Name
orthodenticle homeobox 1
keratin associated protein 5-9
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Keratin Filament
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Protein Binding
Biological Process
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Epidermis Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
103 interactors:
ADAMTSL4
ALPP
ATG9A
BEX2
BMP7
C10orf62
C11orf87
C19orf66
CARKD
CATSPER1
CHIC2
CHRD
CKS1B
CNNM3
COMT
CRCT1
CTSZ
CXCL16
DHRS1
DMRT3
DOCK2
FAH
FAM124B
FAM161A
FAM74A4
FAM76B
GLRX3
GNE
HOXA1
HOXB9
HPCAL1
HSPD1
JOSD1
KLHL38
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE3C
LCE3E
LCE4A
LY6H
MAPKBP1
MEOX2
NCLN
NLK
NMU
NOTCH2NL
NPBWR2
NPDC1
NTM
NTN4
NUFIP2
OTX1
P2RX4
PCSK5
PFKL
PGLS
POM121L8P
PRKAB2
PSMA1
PTPMT1
PVRL2
RAMP3
RGS20
RNF111
SCARB1
SDC3
SDCBP
SLC22A23
SLC25A10
SMCP
SPINK2
SPRY2
TBC1D10C
TBC1D16
TCEA2
TCEANC
TOMM22
TYRO3
WDYHV1
YIPF3
ZBTB24
ZFYVE21
ZNF124
ZNF266
ZNF417
ZNF439
ZNF581
ZNF587
Entrez ID
5013
3846
HPRD ID
08964
01008
Ensembl ID
ENSG00000115507
ENSG00000254997
Uniprot IDs
P32242
P26371
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Keratinization
Keratinocyte Differentiation
Pattern Specification Process
Epidermal Cell Differentiation
Developmental Process
Positive Regulation Of Immune Response To Tumor Cell
Adhesion Of Symbiont To Host
Locomotion
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Muscle Hypertrophy
Organ Development
Cell Recognition
Skin Development
Multicellular Organismal Development
Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin
Anterior/posterior Pattern Specification
Cell Differentiation
System Development
Epidermis Development
Transcription, DNA-templated
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?