LCE4A and RGS20

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE4A	RGS20
Gene Name		late cornified envelope 4A	regulator of G-protein signaling 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane
	Molecular Function		GTPase Activator Activity Protein Binding
	Biological Process	Keratinization	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ADAMTSL4 HOXA1 KRT31 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MEOX2 OTX1 PLSCR1 RGS17 RGS20 RNF111 SMCP SPRY2	33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16
Entrez ID		199834	8601
HPRD ID		17264	06225
Ensembl ID		ENSG00000187170	ENSG00000147509
Uniprot IDs		Q5TA78	H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?		Pattern Specification Process Positive Regulation Of Metabolic Process Embryonic Organ Morphogenesis Inner Ear Morphogenesis Ear Morphogenesis Positive Regulation Of Gene Expression Embryonic Organ Development Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Embryo Development Ear Development Embryonic Morphogenesis Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Termination Of G-protein Coupled Receptor Signaling Pathway Optokinetic Behavior Abducens Nerve Formation Termination Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Facial Nucleus Development Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Semicircular Canal Formation Regulation Of Signal Transduction Embryonic Skeletal System Morphogenesis Negative Regulation Of Signal Transduction Epithelium Development Rhombomere 3 Development Rhombomere 5 Development Metencephalon Development Negative Regulation Of Signaling Developmental Process Ubiquitin-dependent SMAD Protein Catabolic Process Somite Specification Phosphatidylserine Biosynthetic Process Sensory Perception Of Sound Regulation Of Signaling Embryonic Skeletal System Development Sensory Organ Development Diencephalon Morphogenesis Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Hindbrain Development Regulation Of G-protein Coupled Receptor Protein Signaling Pathway	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis
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