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OTX1 and KRTAP4-2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
OTX1
KRTAP4-2
Gene Name
orthodenticle homeobox 1
keratin associated protein 4-2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Keratin Filament
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Biological Process
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
72 interactors:
ADAMTSL4
ALDH3B1
AMOTL2
AQP1
ATG9A
BYSL
C19orf66
CHIC2
CHRD
CRCT1
CREB5
DLGAP2
DOCK2
FAM74A4
GLRX3
GNMT
HOXA1
HPCAL1
HSD3B7
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LASP1
LCE1B
LCE2A
LCE3C
LCE3E
LCE4A
LNX1
MEOX2
NLK
NOTCH2NL
NR1D2
NUFIP2
OTX1
PDE9A
PGLS
PIN1
PLSCR1
POM121L8P
PRKAB2
PRKAG1
PSMA6
PVRL3
RASSF5
RGS20
SLC23A1
SLC25A10
SPATA24
SPATA3
SPRY1
TCEANC
TINAGL1
TRIM42
TXNDC5
TYRO3
WDYHV1
ZBTB24
ZNF124
ZNF20
ZNF417
ZNF559
ZNF581
Entrez ID
5013
85291
HPRD ID
08964
13944
Ensembl ID
ENSG00000115507
ENSG00000244537
Uniprot IDs
P32242
Q9BYR5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Keratinization
Keratinocyte Differentiation
Epidermal Cell Differentiation
Epidermis Development
Transcription, DNA-templated
Epithelium Development
Skin Development
RNA Biosynthetic Process
Organ Development
Tissue Development
Transepithelial Transport
Cellular Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Multicellular Organismal Development
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Apoptotic Cell Clearance
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Transepithelial L-ascorbic Acid Transport
Organic Anion Transport
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?