LCE4A and LCE1D

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		LCE4A	LCE1D
Description		late cornified envelope 4A	late cornified envelope 1D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Epidermis Development Keratinization	Epidermis Development Keratinization Cognition Cellular Response To Calcium Ion
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		79 interacting genes: ADAMTSL4 ALPP CRCT1 CREB5 CYSRT1 FUCA2 GRN HOXA1 HSD3B7 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE5A MDFI MEOX2 NBPF19 NOTCH2NLA NUFIP2 OTX1 P4HB PLSCR1 PLSCR3 RGS17 RGS19 RGS20 RNF111 SLC39A7 SMCP SPRY1 SPRY2 TGM1 TRIM42 TSPAN4 VASN VWC2 ZNF655	69 interacting genes: ADAMTSL4 ALPP AMOT CATSPER1 CHIC2 CRCT1 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MDFI MEOX2 NBPF19 NOTCH2NLA NTAQ1 NUFIP2 PCSK5 PIAS4 RAD54L2 RGS17 RGS20 RNF4 SCARF1 SMCP SPRY1 TGFB1 TRIM42 UBE2I
Entrez ID		199834	353134
HPRD ID		17264	13968
Ensembl ID		ENSG00000187170	ENSG00000172155
Uniprot IDs		Q5TA78	Q5T752
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Epidermis Development Keratinization Tissue Development Hair Cycle Protein Binding Cytosol Lead Ion Binding Identical Protein Binding Mercury Ion Binding Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Lens Fiber Cell Differentiation	Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Protein Binding Negative Regulation Of Protein Localization To Chromatin
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