OTX1 and KRTAP12-4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		OTX1	KRTAP12-4
Gene Name		orthodenticle homeobox 1	keratin associated protein 12-4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Keratin Filament
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: CHIC2 CHRD COMP GEMIN8P4 GRN KCNK16 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4	9 interactors: ARID5A HMGB4 HOXA1 IQUB MEOX2 NOTCH2NL OTX1 PIH1D2 VENTX
Entrez ID		5013	386684
HPRD ID		08964	11200
Ensembl ID		ENSG00000115507	ENSG00000212933
Uniprot IDs		P32242	P60329
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Keratinocyte Differentiation Epithelium Development Epidermis Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Tissue Development Epidermal Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Skin Development Organ Development Developmental Process Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Development Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Developmental Growth Involved In Morphogenesis Negative Regulation Of Signaling Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Multicellular Organismal Development Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway System Development Spindle Localization BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Epithelial Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Organ Morphogenesis Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Developmental Growth Regulation Of MAP Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Growth Regulation Of GTPase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity	Anterior/posterior Pattern Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Optokinetic Behavior Abducens Nerve Formation Pattern Specification Process Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated Facial Nucleus Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Ear Morphogenesis Regulation Of RNA Biosynthetic Process Metencephalon Development Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Semicircular Canal Formation Rhombomere 4 Development Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Multicellular Organismal Development Rhombomere 3 Development Rhombomere 5 Development Hindbrain Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Inner Ear Development Somite Specification Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Morphogenesis Ear Development Embryonic Neurocranium Morphogenesis Outer Ear Morphogenesis Semicircular Canal Morphogenesis Rhombomere Development Facial Nerve Structural Organization Pons Development Regulation Of Cellular Process Facial Nerve Morphogenesis Transcription, DNA-templated Semicircular Canal Development Embryonic Organ Morphogenesis RNA Biosynthetic Process Embryo Development Anatomical Structure Morphogenesis Segment Specification Parasympathetic Nervous System Development Positive Regulation Of Cellular Metabolic Process Anatomical Structure Arrangement Positive Regulation Of Histone Acetylation
Tagcloud ?		17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Difference) ?		17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Intersection) ?