GADD45A and ZNF135

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GADD45A	ZNF135
Gene Name		growth arrest and DNA-damage-inducible, alpha	zinc finger protein 135
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Core Promoter Binding Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Activation Of MAPKKK Activity DNA Repair Negative Regulation Of Protein Kinase Activity Apoptotic Process Cell Cycle Arrest Centrosome Cycle Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Cellular Response To Mechanical Stimulus Cellular Response To Ionizing Radiation Positive Regulation Of P38MAPK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cytoskeleton Organization Regulation Of Cell Morphogenesis
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		65 interactors: ADAP1 ASCC2 AURKA BAG6 C14orf1 CCNB1 CDK1 CDK11A CDKN1A CENPB CHD3 CLEC3B DCTN2 DNAJC13 EEF1A1 EEF1G FAM83D FAS FBN3 FTL GADD45GIP1 GAPDH GBP2 GNB2 HIST1H1A HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 IGHM IGSF21 JMJD1C KHSRP LMO4 MAP3K4 MAPK14 MASP1 MDM2 MICAL1 MIDN MPP1 NPM1 NRBP1 NUCB2 PCNA PFKFB4 PPARA PSMC3 PTN PTPRK QARS RAI1 RBPJ RPS2 RXRA SH3GLB1 SPTBN4 SYNE4 TLE1 TP53 UBE2D1 UBR1 VIM ZHX1 ZNF135	6 interactors: ANXA7 CDKN1A GADD45A GSK3B RAP1B RCC1
Entrez ID		1647	7694
HPRD ID		00528	07242
Ensembl ID		ENSG00000116717	ENSG00000176293
Uniprot IDs		A5JUZ3 P24522	B4DLZ7 P52742 Q8N9M3
PDB IDs		2KG4
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Cell Cycle Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Mitotic Cell Cycle Process Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Organelle Organization DNA Packaging DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Organization Cell Aging Protein Complex Assembly Chromatin Organization Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Death Death Positive Regulation Of Protein Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance DNA Damage Checkpoint Chromatin Assembly Or Disassembly Stress-induced Premature Senescence Immune Response Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Mitotic DNA Damage Checkpoint Immune System Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cell Death Positive Regulation Of Metabolic Process Innate Immune Response Mitotic DNA Integrity Checkpoint Response To Toxic Substance Positive Regulation Of Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Cellular Response To Oxygen Levels	Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase Activity Neurotrophin Signaling Pathway Regulation Of Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Cellular Component Organization Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Phosphorylation Cellular Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Cellular Response To Heat Positive Regulation Of Ras GTPase Activity Regulation Of Phosphorylation Cellular Response To Mechanical Stimulus Cell Cycle Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Ras GTPase Activity Epithelial Cell Differentiation Signal Transduction In Response To DNA Damage Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Response To Growth Factor Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Heat Positive Regulation Of Cell Death Response To Stress Tissue Development Regulation Of Intracellular Signal Transduction Regulation Of Ras Protein Signal Transduction Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Phosphatidylinositol-mediated Signaling Intracellular Signal Transduction
Tagcloud ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?