GADD45A and MICAL1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GADD45A	MICAL1
Gene Name		growth arrest and DNA-damage-inducible, alpha	microtubule associated monooxygenase, calponin and LIM domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Intermediate Filament
	Molecular Function	Core Promoter Binding Protein Binding	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen SH3 Domain Binding Rab GTPase Binding FAD Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Activation Of MAPKKK Activity DNA Repair Negative Regulation Of Protein Kinase Activity Apoptotic Process Cell Cycle Arrest Centrosome Cycle Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Cellular Response To Mechanical Stimulus Cellular Response To Ionizing Radiation Positive Regulation Of P38MAPK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process	Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Signal Transduction Sulfur Oxidation Actin Filament Depolymerization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		65 interactors: ADAP1 ASCC2 AURKA BAG6 C14orf1 CCNB1 CDK1 CDK11A CDKN1A CENPB CHD3 CLEC3B DCTN2 DNAJC13 EEF1A1 EEF1G FAM83D FAS FBN3 FTL GADD45GIP1 GAPDH GBP2 GNB2 HIST1H1A HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 IGHM IGSF21 JMJD1C KHSRP LMO4 MAP3K4 MAPK14 MASP1 MDM2 MICAL1 MIDN MPP1 NPM1 NRBP1 NUCB2 PCNA PFKFB4 PPARA PSMC3 PTN PTPRK QARS RAI1 RBPJ RPS2 RXRA SH3GLB1 SPTBN4 SYNE4 TLE1 TP53 UBE2D1 UBR1 VIM ZHX1 ZNF135	16 interactors: ABL1 CRK EHD1 GADD45A GRB2 GSK3B NEDD9 PIK3R3 PTK2 RAB10 RAB1A RAB1B RPS6KA6 SRC TAB1 VIM
Entrez ID		1647	64780
HPRD ID		00528	06183
Ensembl ID		ENSG00000116717	ENSG00000135596
Uniprot IDs		A5JUZ3 P24522	Q8TDZ2
PDB IDs		2KG4	1WYL 2CO8 2DK9
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Cell Cycle Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Mitotic Cell Cycle Process Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Organelle Organization DNA Packaging DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Organization Cell Aging Protein Complex Assembly Chromatin Organization Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Death Death Positive Regulation Of Protein Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance DNA Damage Checkpoint Chromatin Assembly Or Disassembly Stress-induced Premature Senescence Immune Response Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Mitotic DNA Damage Checkpoint Immune System Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cell Death Positive Regulation Of Metabolic Process Innate Immune Response Mitotic DNA Integrity Checkpoint Response To Toxic Substance Positive Regulation Of Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Cellular Response To Oxygen Levels	Fc Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Regulation Of Phosphorylation Signal Transduction Regulation Of MAPK Cascade Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Signaling Cell Morphogenesis Involved In Differentiation Cell Communication Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Protein Metabolic Process Axonogenesis Cell Development Cellular Response To Peptide Hormone Stimulus Axon Development Cellular Response To Growth Factor Stimulus Response To Stimulus Cellular Response To Peptide Intracellular Signal Transduction Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Growth Factor Neuron Development Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Vesicle-mediated Transport Neuron Projection Morphogenesis Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Cell Morphogenesis Generation Of Neurons Positive Regulation Of Protein Phosphorylation Neuron Differentiation Blood Coagulation Cellular Response To Insulin Stimulus Hemostasis Regulation Of Protein Kinase Activity Ras Protein Signal Transduction Cell Projection Organization Neurogenesis Response To Peptide Hormone
Tagcloud ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?