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GADD45A and ADAP1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
GADD45A
ADAP1
Gene Name
growth arrest and DNA-damage-inducible, alpha
ArfGAP with dual PH domains 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Cytoplasm
Plasma Membrane
Molecular Function
Core Promoter Binding
Protein Binding
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Inositol 1,3,4,5 Tetrakisphosphate Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Activation Of MAPKKK Activity
DNA Repair
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Cell Cycle Arrest
Centrosome Cycle
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Cell Surface Receptor Signaling Pathway
Regulation Of ARF GTPase Activity
Regulation Of GTPase Activity
Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
65 interactors:
ADAP1
ASCC2
AURKA
BAG6
C14orf1
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
DCTN2
DNAJC13
EEF1A1
EEF1G
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
HIST1H1A
HIST1H2AL
HIST2H2BE
HIST3H3
HIST4H4
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
23 interactors:
ANP32A
AP3B2
CSNK1A1
DVL3
GADD45A
GOLGA2
GSK3B
NCL
PIK3CA
PRKCA
PRKCE
PRKCI
PRKCZ
PRKD1
PSME3
PURA
RANBP9
RPS9
SDCBP2
SF3A3
SRSF2
SUB1
SUPV3L1
Entrez ID
1647
11033
HPRD ID
00528
09733
Ensembl ID
ENSG00000116717
ENSG00000105963
Uniprot IDs
A5JUZ3
P24522
O75689
PDB IDs
2KG4
3FEH
3FM8
3LJU
3MDB
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Cell Cycle
Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cellular Response To Organic Substance
Regulation Of Protein Metabolic Process
Organelle Organization
DNA Packaging
DNA Conformation Change
Negative Regulation Of Cellular Metabolic Process
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromosome Organization
Cell Aging
Protein Complex Assembly
Chromatin Organization
Negative Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Cell Death
Death
Positive Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Chromatin Assembly Or Disassembly
Stress-induced Premature Senescence
Immune Response
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Mitotic DNA Damage Checkpoint
Immune System Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Innate Immune Response
Mitotic DNA Integrity Checkpoint
Response To Toxic Substance
Positive Regulation Of Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Oxygen Levels
Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Intracellular Transport
Regulation Of Cellular Amino Acid Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Ketone Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Establishment Of Localization In Cell
Positive Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Response To Growth Factor
Positive Regulation Of Protein Modification Process
Positive Regulation Of Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Negative Regulation Of Cell Death
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Phosphorylation
Cellular Localization
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Cell Death
Positive Regulation Of Wnt Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Phosphorylation
Epidermal Growth Factor Receptor Signaling Pathway
Protein Phosphorylation
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of MAPK Cascade
Positive Regulation Of Cell Adhesion
Regulation Of Glucose Import
Signaling
Cellular Response To Fibroblast Growth Factor Stimulus
Cell Communication
Regulation Of Metabolic Process
Platelet Activation
Response To Fibroblast Growth Factor
Negative Regulation Of Glial Cell Apoptotic Process
Anatomical Structure Morphogenesis
Positive Regulation Of Phospholipase Activity
Tagcloud
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?