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CLTC and GRIN1
Number of citations of the paper that reports this interaction (PMID
10862698
)
203
Data Source:
HPRD
(in vivo)
CLTC
GRIN1
Gene Name
clathrin, heavy chain (Hc)
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Spindle
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Clathrin Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Clathrin-coated Endocytic Vesicle Membrane
Vesicle
Trans-Golgi Network Membrane
Melanosome
Intracellular Membrane-bounded Organelle
Protein Complex
Extracellular Vesicular Exosome
Clathrin Complex
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Synaptic Vesicle
Cell Surface
Postsynaptic Density
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Dendrite Membrane
Neuron Projection
Synaptic Cleft
Terminal Bouton
Dendritic Spine
Synapse
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Molecular Function
Double-stranded RNA Binding
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Clathrin Light Chain Binding
Poly(A) RNA Binding
N-methyl-D-aspartate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Glycine Binding
Glutamate Binding
Enzyme Binding
Voltage-gated Cation Channel Activity
Glutamate Receptor Binding
Neurotransmitter Binding
Protein Heterodimerization Activity
Biological Process
Osteoblast Differentiation
Intracellular Protein Transport
Post-Golgi Vesicle-mediated Transport
Receptor-mediated Endocytosis
Mitotic Nuclear Division
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Transferrin Transport
Membrane Organization
Negative Regulation Of Hyaluronan Biosynthetic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Conditioned Taste Aversion
Suckling Behavior
Response To Amphetamine
Cation Transport
Cellular Calcium Ion Homeostasis
Synaptic Transmission
Axon Guidance
Respiratory Gaseous Exchange
Long-term Memory
Adult Locomotory Behavior
Olfactory Learning
Visual Learning
Propylene Metabolic Process
Sensory Perception Of Pain
Pons Maturation
Cerebral Cortex Development
Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transport
Social Behavior
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Membrane Potential
Positive Regulation Of Apoptotic Process
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Respiratory Gaseous Exchange
Response To Ethanol
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Ephrin Receptor Signaling Pathway
Regulation Of Long-term Neuronal Synaptic Plasticity
Rhythmic Process
Regulation Of Dendrite Morphogenesis
Regulation Of Axonogenesis
Protein Tetramerization
Response To Calcium Ion
Regulation Of Synapse Assembly
Calcium Ion Homeostasis
Regulation Of Excitatory Postsynaptic Membrane Potential
Prepulse Inhibition
Male Mating Behavior
Response To Fungicide
Calcium Ion Transmembrane Transport
Cellular Response To Manganese Ion
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Formation of annular gap junctions
EPH-ephrin mediated repulsion of cells
Axon guidance
Gap junction degradation
Gap junction trafficking and regulation
Gap junction trafficking
WNT5A-dependent internalization of FZD4
EPH-Ephrin signaling
Signaling by Wnt
PCP/CE pathway
beta-catenin independent WNT signaling
EPHB-mediated forward signaling
Axon guidance
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
EPH-Ephrin signaling
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Meperidine
Orphenadrine
Dcka, 5,7-Dichlorokynurenic Acid
D-Serine
Cycloleucine
Milnacipran
Agmatine
Diseases
GWAS
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Protein-Protein Interactions
60 interactors:
AMPH
AP1B1
AP1G1
AP2A2
AP2B1
AP3B1
AP3B2
ARMCX3
ARR3
ARRB1
ARRB2
C10orf88
CLINT1
CLTA
CLTB
DNAJC6
EHD1
EP300
EPN1
EPN2
ERG
FYN
GAK
GGA1
GGA2
GGA3
GRIN1
GRIN2D
HGS
HIP1
HIP1R
ITSN1
KIT
LDLRAP1
MAP3K10
NCALD
NDRG1
OCRL
PICALM
PPP1CA
PPP1CC
PRKACA
PXN
QARS
SCYL2
SNX5
SNX9
SRC
STAM
STAMBP
SYNJ1
TFAP2A
TNK2
TOM1
VCL
WNK1
XRCC6
YWHAG
YWHAQ
ZFYVE9
53 interactors:
ACTN2
AKAP9
CALM1
CAMK2A
CAMK2G
CANX
CDH2
CIT
CLTC
CTNNB1
DLG2
DLG3
DLG4
DLGAP4
DNM1
DRD1
DUSP4
EPHB2
EPHB4
FUS
FYN
GRIN2A
GRIN2B
GRIN2D
GRIN3A
HNRNPU
HRAS
HSPA1A
INA
LNX1
LRP8
MAP2
MAP2K2
MYH9
NANOS1
NEFL
NF1
PLAT
PLCG1
PPP2R1A
PPP2R2A
PRKCA
PRKCB
PRKCE
PRKCG
RAP2A
RPS6KA3
SP3
SPTAN1
SYNGAP1
TJP1
TRAF3
TUBA4B
Entrez ID
1213
2902
HPRD ID
00350
15926
Ensembl ID
ENSG00000141367
ENSG00000176884
Uniprot IDs
Q00610
Q05586
Q59GW0
Q5VSF9
PDB IDs
2XZG
4G55
2HQW
2NR1
3BYA
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Endocytosis
Transport
Establishment Of Localization In Cell
Intracellular Transport
Cellular Localization
Intracellular Protein Transport
Cellular Protein Localization
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
ERBB Signaling Pathway
Protein Transport
Signaling
Establishment Of Protein Localization
Cell Communication
Enzyme Linked Receptor Protein Signaling Pathway
Protein Localization
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Endocytosis
Negative Regulation Of ERBB Signaling Pathway
Cellular Response To Growth Factor Stimulus
Regulation Of Signaling
Response To Growth Factor
Membrane Organization
Positive Regulation Of Transport
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Stimulus
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Synaptic Transmission
Endosomal Transport
Negative Regulation Of Signaling
Post-Golgi Vesicle-mediated Transport
Signal Transduction
Regulation Of Defense Response To Virus By Virus
Nervous System Development
Receptor-mediated Endocytosis
Regulation Of Cellular Component Organization
Cell-cell Signaling
Response To Stimulus
Positive Regulation Of Receptor-mediated Endocytosis
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Receptor Internalization
Regulation Of Protein Metabolic Process
Cell Surface Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Positive Regulation Of Endocytosis
Synaptic Transmission
Cell-cell Signaling
Nervous System Development
Signaling
Locomotion
Cell Communication
Neurogenesis
Cell Differentiation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Organic Substance
Generation Of Neurons
Neuron Projection Development
Neuron Development
Developmental Process
Cell Development
Neuron Differentiation
Response To External Stimulus
Signal Transduction
Cell Projection Organization
Movement Of Cell Or Subcellular Component
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
System Development
Cellular Response To Stimulus
Anatomical Structure Development
Axon Development
Axon Guidance
Regulation Of Synaptic Transmission
Regulation Of Synaptic Plasticity
Neuron Projection Morphogenesis
Cell Surface Receptor Signaling Pathway
Axonogenesis
Cellular Response To Organic Substance
Response To Wounding
Cell Morphogenesis Involved In Neuron Differentiation
Cell Morphogenesis Involved In Differentiation
Learning
Response To Stimulus
Regulation Of Signaling
Chemotaxis
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Response To Abiotic Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Cell Projection Morphogenesis
Single-organism Behavior
Cellular Response To Growth Factor Stimulus
Learning Or Memory
Tagcloud
?
alk
clathrin
contribution
deregulated
diffuse
dlbcl
dlbcls
encoding
feature
formed
lm1
lymphoma
lymphomas
maintenance
nanomolar
nod
nvp
otherwise
providing
rationale
refractory
repressed
scid
signalling
subtype
sustained
tae684
thereby
xenotransplant
Tagcloud (Difference)
?
alk
clathrin
contribution
deregulated
diffuse
dlbcl
dlbcls
encoding
feature
formed
lm1
lymphoma
lymphomas
maintenance
nanomolar
nod
nvp
otherwise
providing
rationale
refractory
repressed
scid
signalling
subtype
sustained
tae684
thereby
xenotransplant
Tagcloud (Intersection)
?