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CLTC and ITSN1
Number of citations of the paper that reports this interaction (PubMedID
22558309
)
58
Data Source:
BioGRID
(two hybrid)
CLTC
ITSN1
Description
clathrin heavy chain
intersectin 1
Image
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Endosome
Trans-Golgi Network
Spindle
Cytosol
Cytoskeleton
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Membrane
Clathrin Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Cytoplasmic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Trans-Golgi Network Membrane
Protein-containing Complex
Centriolar Satellite
Endolysosome Membrane
Melanosome
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Clathrin Complex
Mitotic Spindle
Extracellular Vesicle
Mitotic Spindle Microtubule
Nucleus
Nuclear Envelope
Cytoplasm
Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Endomembrane System
Membrane
Lamellipodium
Cytoplasmic Vesicle
Presynaptic Membrane
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Recycling Endosome
Apical Dendrite
Intracellular Vesicle
Postsynaptic Endocytic Zone
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
Molecular Function
RNA Binding
Double-stranded RNA Binding
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Clathrin Light Chain Binding
Low-density Lipoprotein Particle Receptor Binding
Disordered Domain Specific Binding
Ubiquitin-specific Protease Binding
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Molecular Adaptor Activity
Proline-rich Region Binding
Biological Process
Mitotic Cell Cycle
Osteoblast Differentiation
Intracellular Protein Transport
Receptor-mediated Endocytosis
Autophagy
Vesicle-mediated Transport
Receptor Internalization
Transferrin Transport
Retrograde Transport, Endosome To Golgi
Clathrin Coat Assembly
Cell Division
Regulation Of Mitotic Spindle Organization
Clathrin Coat Disassembly
Clathrin-dependent Endocytosis
Amyloid-beta Clearance By Transcytosis
Negative Regulation Of Hyaluronan Biosynthetic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Exocytosis
Endocytosis
Intracellular Protein Localization
Regulation Of Cell Communication
Protein Transport
Endosomal Transport
Regulation Of Signaling
Intracellular Signal Transduction
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Growth Hormone Secretion
Positive Regulation Of Dendritic Spine Development
Regulation Of Postsynapse Organization
Clathrin-dependent Synaptic Vesicle Endocytosis
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Caveolin-mediated Endocytosis
Pathways
Entry of Influenza Virion into Host Cell via Endocytosis
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
RHOU GTPase cycle
RHOV GTPase cycle
ALK mutants bind TKIs
Signaling by ALK fusions and activated point mutants
NRAGE signals death through JNK
EPHB-mediated forward signaling
EPHB-mediated forward signaling
G alpha (12/13) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
CDC42 GTPase cycle
RHOQ GTPase cycle
RHOG GTPase cycle
Drugs
Diseases
GWAS
Bitter non-alcoholic beverage consumption (
31046077
)
Educational attainment (
25201988
)
Height (
31562340
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
QT interval (
29213071
)
Red blood cell count (
32888494
)
Red cell distribution width (
27863252
32888494
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
70 interacting genes:
ACO1
AFTPH
AMPH
ANXA1
AP1B1
AP1G1
AP3B1
AP3B2
ARF6
ARMCX3
ARR3
ARRB1
ARRB2
BTG3
C10orf88
CEBPA
CLINT1
CLTA
CLTB
DNAJC6
DSCAM
DSCR9
DUX4
EPN1
EPN2
ERG
FYN
GAK
GGA1
GGA2
GGA3
GRIN1
GRIN2D
HGS
HIP1
HIP1R
ITSN1
KIT
LDLRAP1
MAP3K10
MAU2
NCALD
NDRG1
OCRL
OPTN
PICALM
PPP1CC
PRKACA
PXN
QARS1
RIPK4
SCYL2
SMAP1
SNX5
SNX9
SPATC1L
SRC
STAMBP
SUMO2
SYNJ1
TFAP2A
TNK2
TOM1
USP7
VCL
WNK1
XRCC6
YWHAG
YWHAQ
ZFYVE9
140 interacting genes:
AGFG1
AGFG2
AJUBA
ANKRD36
ANKRD54
ARF6
ARFIP2
ARHGAP31
ASAP2
BECN1
BFSP1
BRCC3
BRWD3
CCDC24
CCNO
CDC42
CEP85L
CLIP2
CLTC
COG4
CSNK2B
CYTH1
CYTH3
DAB1
DAB2
DES
DISC1
DLGAP1
DNAI7
DNAJA2
DNM1
DNM2
DST
DYNC1H1
EEF1A1
EPHB2
EPN2
EPS15
EXOC1
FCHO1
FCHO2
FCHSD2
FNBP1
FNBP4
GAREM2
GCC1
GFAP
GNPTG
GOLGA5
HIP1
HNRNPK
HRAS
IFT74
ITSN2
KHDRBS1
KIF16B
KIF5A
KIF5C
KRT222
LMO3
LMO4
MAP3K20
MAPK6
MAPK8IP2
MED4
MRPL20
MTUS2
MYH14
NASP
NEFL
NEFM
NEMF
PACSIN3
PDCD6IP
PDE2A
PDZD8
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
PRRG4
RAB11FIP2
RAB5A
RABEP1
RAI14
RALBP1
REPS1
REPS2
RIN1
RNF40
RPS6KA5
RRBP1
SCAI
SCAMP1
SCOC
SF3B4
SH3GL2
SHANK3
SIAH1
SMARCC2
SMC1A
SNAP23
SNAP25
SNRNP70
SNX5
SNX6
SOS1
SOS2
SPDL1
SPECC1
SPRY2
SPTAN1
SPTBN1
STON2
SYNC
SYNE1
SYNJ1
SYNJ2
TK1
TRAF3IP1
TRIM5
TRIM8
TRPM7
TSG101
TTC27
UBC
UBE2K
UNC119
VLDLR
WASL
WBP11
WHAMM
ZFC3H1
ZFPM2
ZMYM5
Entrez ID
1213
6453
HPRD ID
00350
03898
Ensembl ID
ENSG00000141367
ENSG00000205726
Uniprot IDs
A0A087WVQ6
Q00610
A7XZY7
F8W7U0
Q15811
Q6PD56
PDB IDs
2XZG
4G55
6E4L
6QNN
6QNP
7BN1
7BN2
7ZX4
9C0Y
9C0Z
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
5HZI
5HZJ
5HZK
6GBU
6H5T
Enriched GO Terms of Interacting Partners
?
Endocytosis
Clathrin Binding
Vesicle-mediated Transport
Import Into Cell
Clathrin-coated Vesicle
Cytoplasmic Vesicle
Clathrin-coated Pit
Receptor-mediated Endocytosis
Early Endosome
Synaptic Vesicle Endocytosis
Regulation Of Vesicle-mediated Transport
Cytosol
Presynaptic Endocytosis
Endosome
Establishment Of Localization In Cell
Intracellular Transport
Regulation Of Endocytosis
Clathrin-dependent Endocytosis
Regulation Of Receptor-mediated Endocytosis
Cellular Localization
Establishment Of Protein Localization
Clathrin Vesicle Coat
Clathrin Coat Assembly
Clathrin Heavy Chain Binding
Phosphatidylinositol Binding
Protein Transport
Protein Localization To Cell Surface
Intracellular Protein Localization
Cytoplasm
Vesicle-mediated Transport In Synapse
Clathrin-coated Vesicle Membrane
Regulation Of Transport
Clathrin Coat Of Coated Pit
Early Endosome Membrane
Receptor Internalization
Intracellular Protein Transport
Golgi Apparatus
Cytoplasmic Vesicle Membrane
Presynapse
Phospholipid Binding
Regulation Of Clathrin Coat Assembly
Synaptic Vesicle Uncoating
Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Endosomal Transport
Membrane Coat
Perinuclear Region Of Cytoplasm
Protein Domain Specific Binding
Positive Regulation Of Cellular Component Organization
Clathrin Coat Disassembly
Clathrin Adaptor Activity
Endocytosis
Vesicle-mediated Transport
Import Into Cell
Cytoplasm
Cytosol
Establishment Of Localization In Cell
Clathrin-coated Pit
Clathrin Coat Assembly
Cytoskeleton Organization
Organelle Organization
Cytoskeleton
Regulation Of Cellular Component Organization
Receptor-mediated Endocytosis
Organelle Localization
Membrane Organization
Cellular Component Assembly
Clathrin-coated Vesicle
Protein Transport
Clathrin-dependent Endocytosis
Intermediate Filament-based Process
Cellular Localization
Establishment Of Organelle Localization
Intracellular Transport
Negative Regulation Of Cellular Component Organization
Synaptic Vesicle Endocytosis
Establishment Of Protein Localization
Regulation Of Protein Localization To Cell Periphery
Presynaptic Endocytosis
Vesicle-mediated Transport In Synapse
Intermediate Filament Cytoskeleton Organization
Intracellular Protein Localization
Protein-containing Complex Assembly
Clathrin Coat Of Coated Pit
Intermediate Filament Cytoskeleton
Protein-containing Complex Organization
Structural Constituent Of Cytoskeleton
Post-Golgi Vesicle-mediated Transport
Glutamatergic Synapse
Microtubule Binding
Establishment Of Vesicle Localization
Endosomal Transport
Cell Cortex
Cytoplasmic Vesicle
Golgi Vesicle Transport
Regulation Of Protein Localization To Plasma Membrane
Vesicle Localization
Cytoskeleton-dependent Intracellular Transport
Cell Projection Organization
Mitotic Cytokinesis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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