CLTC and CLINT1

Number of citations of the paper that reports this interaction (PMID 12429846)
33

Data Source:
HPRD (in vitro)

		CLTC	CLINT1
Gene Name		clathrin, heavy chain (Hc)	clathrin interactor 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Spindle Cytosol Plasma Membrane Focal Adhesion Membrane Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Vesicle Trans-Golgi Network Membrane Melanosome Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome Clathrin Complex	Nucleoplasm Golgi Apparatus Cytosol Membrane Clathrin-coated Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Double-stranded RNA Binding Structural Molecule Activity Protein Binding Protein Kinase Binding Clathrin Light Chain Binding Poly(A) RNA Binding	Protein Binding Lipid Binding Clathrin Binding
	Biological Process	Osteoblast Differentiation Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Mitotic Nuclear Division Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Receptor Internalization Transferrin Transport Membrane Organization Negative Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Protein Localization To Plasma Membrane	Post-Golgi Vesicle-mediated Transport Endocytosis Clathrin Coat Assembly Membrane Organization
Pathways		Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Axon guidance Gap junction degradation Gap junction trafficking and regulation Gap junction trafficking WNT5A-dependent internalization of FZD4 EPH-Ephrin signaling Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		60 interactors: AMPH AP1B1 AP1G1 AP2A2 AP2B1 AP3B1 AP3B2 ARMCX3 ARR3 ARRB1 ARRB2 C10orf88 CLINT1 CLTA CLTB DNAJC6 EHD1 EP300 EPN1 EPN2 ERG FYN GAK GGA1 GGA2 GGA3 GRIN1 GRIN2D HGS HIP1 HIP1R ITSN1 KIT LDLRAP1 MAP3K10 NCALD NDRG1 OCRL PICALM PPP1CA PPP1CC PRKACA PXN QARS SCYL2 SNX5 SNX9 SRC STAM STAMBP SYNJ1 TFAP2A TNK2 TOM1 VCL WNK1 XRCC6 YWHAG YWHAQ ZFYVE9	12 interactors: AP1G1 AP2A1 AP2B1 CALM1 CLTC DNM1 EPS15 GGA1 GGA2 GGA3 JUN YWHAG
Entrez ID		1213	9685
HPRD ID		00350	06273
Ensembl ID		ENSG00000141367	ENSG00000113282
Uniprot IDs		Q00610	Q14677
PDB IDs		2XZG 4G55	1XGW 2QY7 2V8S
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Transport Establishment Of Localization In Cell Intracellular Transport Cellular Localization Intracellular Protein Transport Cellular Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport ERBB Signaling Pathway Protein Transport Signaling Establishment Of Protein Localization Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Protein Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Endocytosis Negative Regulation Of ERBB Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Signaling Response To Growth Factor Membrane Organization Positive Regulation Of Transport Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Synaptic Transmission Endosomal Transport Negative Regulation Of Signaling Post-Golgi Vesicle-mediated Transport Signal Transduction Regulation Of Defense Response To Virus By Virus Nervous System Development Receptor-mediated Endocytosis Regulation Of Cellular Component Organization Cell-cell Signaling Response To Stimulus Positive Regulation Of Receptor-mediated Endocytosis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Receptor Internalization Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Positive Regulation Of Endocytosis	Establishment Of Localization In Cell Protein Transport Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Protein Localization Cellular Protein Localization Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin-mediated Endocytosis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Antigen Processing And Presentation Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Receptor-mediated Endocytosis Golgi To Endosome Transport Membrane Organization Regulation Of Protein Autophosphorylation Response To External Stimulus Endosomal Transport Axon Development Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Neurotrophin Signaling Pathway Receptor Internalization Regulation Of Immune System Process Cytoplasmic Transport Organelle Organization Immune System Process Nervous System Development Negative Regulation Of Protein Phosphorylation Cell Differentiation
Tagcloud ?		alk clathrin contribution deregulated diffuse dlbcl dlbcls encoding feature formed lm1 lymphoma lymphomas maintenance nanomolar nod nvp otherwise providing rationale refractory repressed scid signalling subtype sustained tae684 thereby xenotransplant	02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc
Tagcloud (Difference) ?		alk clathrin contribution deregulated diffuse dlbcl dlbcls encoding feature formed lm1 lymphoma lymphomas maintenance nanomolar nod nvp otherwise providing rationale refractory repressed scid signalling subtype sustained tae684 thereby xenotransplant	02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc
Tagcloud (Intersection) ?