Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
GABARAPL2 and SQSTM1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)
HPRD
(two hybrid)
GABARAPL2
SQSTM1
Gene Name
GABA(A) receptor-associated protein-like 2
sequestosome 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Pre-autophagosomal Structure
Autophagic Vacuole Membrane
Intracellular
Cytoplasm
Autophagic Vacuole
Golgi Apparatus
Cytosol
Extrinsic Component Of Membrane
Cytoplasmic Vesicle
Pre-autophagosomal Structure
Cytoplasmic MRNA Processing Body
Nucleoplasm
Cytoplasm
Lysosome
Late Endosome
Autophagic Vacuole
Endoplasmic Reticulum
Cytosol
Inclusion Body
Aggresome
PML Body
Cytoplasmic Vesicle
Extracellular Vesicular Exosome
Molecular Function
SNARE Binding
Protein Binding
Microtubule Binding
Beta-tubulin Binding
GABA Receptor Binding
ATPase Binding
Protein Serine/threonine Kinase Activity
Protein Kinase C Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Receptor Tyrosine Kinase Binding
SH2 Domain Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Binding
K63-linked Polyubiquitin Binding
Biological Process
Autophagic Vacuole Assembly
Mitochondrion Degradation
Intra-Golgi Vesicle-mediated Transport
Autophagy
Cellular Response To Nitrogen Starvation
Protein Transport
Positive Regulation Of ATPase Activity
Nucleophagy
Membrane Fusion
Negative Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Phosphorylation
Immune System Process
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Response To Stress
Protein Localization
Endosomal Transport
Macroautophagy
Positive Regulation Of Macroautophagy
Cell Differentiation
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Ras Protein Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Protein Heterooligomerization
Apoptotic Signaling Pathway
Pathways
Signaling by Interleukins
Signalling by NGF
NF-kB is activated and signals survival
p75NTR recruits signalling complexes
Cell death signalling via NRAGE, NRIF and NADE
NRIF signals cell death from the nucleus
p75NTR signals via NF-kB
Cytokine Signaling in Immune system
Interleukin-1 signaling
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-Protein Interactions
50 interactors:
AAMP
AGTRAP
AHNAK2
APP
ARFGAP1
ATG13
ATG3
ATG4A
ATG4B
ATG4D
ATG7
BCL2L13
CALCOCO1
CALCOCO2
CCDC155
CLN8
EGFR
FUNDC1
GIMAP6
GOSR1
KBTBD7
KIAA1958
KLHL5
KRTAP10-7
KRTAP10-9
LRSAM1
MAP1LC3B
MLX
NBR1
NSF
PTPRA
RAP1A
RAP2A
RCN2
RPS2
SGTA
SIK2
SQSTM1
TBC1D25
TBC1D5
TBC1D9
TBC1D9B
TNIP1
TP53INP2
TSR2
UBA5
ULK1
ULK2
VDR
YWHAZ
74 interactors:
ATXN3
BCL2
BMPR1B
BPTF
CALM1
CAMK2A
CCNB1
CDC37
CDK1
CSNK2A1
DAZAP2
EEF1D
EGLN3
FKBP4
GABARAPL1
GABARAPL2
GABRR1
GABRR2
GEMIN4
GRB14
GRIA1
GRIA2
GRIA3
IRAK1
KCNAB2
KEAP1
LCK
LINC00341
MALT1
MAP1LC3A
MAP1LC3B
MAP2K5
MAP3K3
MAPK14
MBP
MEIS2
MLH1
NBR1
NCOR1
NR2F2
NTRK1
NTRK2
NTRK3
OPTN
PAWR
PIK3CA
PPHLN1
PRKCI
PRKCZ
RAD23A
RELN
RIPK1
RPL37
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SNCA
STXBP1
TGFBR1
TKT
TOE1
TP53
TRAF6
TRIM55
TRIM63
TTN
UBA52
UBB
UBC
ULK1
ULK2
YWHAZ
Entrez ID
11345
8878
HPRD ID
16246
03319
Ensembl ID
ENSG00000034713
ENSG00000161011
Uniprot IDs
P60520
Q13501
PDB IDs
1Q02
2JY7
2JY8
2K0B
2KNV
Enriched GO Terms of Interacting Partners
?
Autophagy
Macroautophagy
Response To Starvation
Cellular Response To Nutrient Levels
Cellular Response To Starvation
Autophagic Vacuole Assembly
Cellular Response To Extracellular Stimulus
Response To Nutrient Levels
Response To Extracellular Stimulus
Vacuole Organization
Mitochondrion Degradation
Organelle Disassembly
Nucleophagy
Membrane Organization
Positive Regulation Of Autophagy
Response To Stress
Cellular Response To Nitrogen Starvation
Catabolic Process
Regulation Of Autophagy
Response To External Stimulus
Protein Localization
Establishment Of Protein Localization
Protein Delipidation
Mitochondrion Organization
Cellular Response To Stress
Positive Regulation Of Metabolic Process
Organelle Assembly
C-terminal Protein Lipidation
Establishment Of Protein Localization To Membrane
Protein Localization To Membrane
Protein Transport
Positive Regulation Of Cellular Metabolic Process
Intracellular Transport
Cellular Localization
Cell Communication
Positive Regulation Of Macroautophagy
Cellular Component Assembly
Response To Stimulus
Establishment Of Localization In Cell
Cellular Response To Stimulus
Protein Targeting To Membrane
Regulation Of Signaling
Regulation Of Signal Transduction
Organelle Organization
Cellular Metabolic Process
Protein Lipidation
Lipoprotein Biosynthetic Process
Negative Regulation Of Collateral Sprouting
Positive Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Cell Communication
Response To Growth Factor
Cellular Response To Growth Factor Stimulus
Cellular Response To Stimulus
Response To Stimulus
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Phosphorylation
Response To Stress
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Kinase Activity
Phosphorylation
Cellular Response To Organic Substance
Regulation Of Kinase Activity
Positive Regulation Of Protein Kinase Activity
Signal Transduction
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Transferase Activity
Positive Regulation Of Kinase Activity
Regulation Of Cell Death
Negative Regulation Of Cell Death
Response To Organic Substance
Regulation Of Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Cellular Metabolic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
Protein Phosphorylation
Activation Of Protein Kinase Activity
Membrane Organization
Neurotrophin TRK Receptor Signaling Pathway
Cellular Component Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Cellular Response To Stress
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Intersection)
?