GABARAPL2 and SIK2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GABARAPL2	SIK2
Gene Name		GABA(A) receptor-associated protein-like 2	salt-inducible kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Cytoplasm Autophagic Vacuole Golgi Apparatus Cytosol Extrinsic Component Of Membrane Cytoplasmic Vesicle	Nucleus Cytoplasm
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Positive Regulation Of ATPase Activity Nucleophagy Membrane Fusion Negative Regulation Of Proteasomal Protein Catabolic Process	Protein Phosphorylation Insulin Receptor Signaling Pathway Intracellular Signal Transduction Regulation Of Insulin Receptor Signaling Pathway Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: AAMP AGTRAP AHNAK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CCDC155 CLN8 EGFR FUNDC1 GIMAP6 GOSR1 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MLX NBR1 NSF PTPRA RAP1A RAP2A RCN2 RPS2 SGTA SIK2 SQSTM1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP2 TSR2 UBA5 ULK1 ULK2 VDR YWHAZ	6 interactors: APP CRTC2 GABARAPL2 HDAC5 IRS1 VCP
Entrez ID		11345	23235
HPRD ID		16246	12348
Ensembl ID		ENSG00000034713
Uniprot IDs		P60520	Q9H0K1
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Starvation Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Nucleophagy Membrane Organization Positive Regulation Of Autophagy Response To Stress Cellular Response To Nitrogen Starvation Catabolic Process Regulation Of Autophagy Response To External Stimulus Protein Localization Establishment Of Protein Localization Protein Delipidation Mitochondrion Organization Cellular Response To Stress Positive Regulation Of Metabolic Process Organelle Assembly C-terminal Protein Lipidation Establishment Of Protein Localization To Membrane Protein Localization To Membrane Protein Transport Positive Regulation Of Cellular Metabolic Process Intracellular Transport Cellular Localization Cell Communication Positive Regulation Of Macroautophagy Cellular Component Assembly Response To Stimulus Establishment Of Localization In Cell Cellular Response To Stimulus Protein Targeting To Membrane Regulation Of Signaling Regulation Of Signal Transduction Organelle Organization Cellular Metabolic Process Protein Lipidation Lipoprotein Biosynthetic Process Negative Regulation Of Collateral Sprouting Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity	Positive Regulation Of Metabolic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Cellular Biosynthetic Process Response To Stress Regulation Of Proteolysis Histone H3-K9 Acetylation Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Cellular Component Assembly Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Collateral Sprouting In Absence Of Injury Chemical Homeostasis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Metabolic Process Glucose Homeostasis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Insulin Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Regulation Of Catalytic Activity Cellular Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein Deubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hydrolase Activity Axon Choice Point Recognition Protein Hexamerization Protein Homooligomerization Regulation Of Binding Golgi Vesicle Transport Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Response To Insulin Positive Regulation Of Proteolysis Neuron Remodeling Cellular Response To Peptide Hormone Stimulus Aggresome Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Peptide Positive Regulation Of Fatty Acid Beta-oxidation Translesion Synthesis Positive Regulation Of Transcription, DNA-templated Defense Response Negative Regulation Of Proteolysis
Tagcloud ?			43delta abrogated adipocyte amp ampk autophagosome autophagosomes autophagy belonging coordinated deacetylation determinant elusive hdac6 hormones indispensable interplay k53q k53r lys lysosome mimetic nonacetylatable nutrients pool restores switch threonine uncover
Tagcloud (Difference) ?			43delta abrogated adipocyte amp ampk autophagosome autophagosomes autophagy belonging coordinated deacetylation determinant elusive hdac6 hormones indispensable interplay k53q k53r lys lysosome mimetic nonacetylatable nutrients pool restores switch threonine uncover
Tagcloud (Intersection) ?