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GABARAPL2 and CDC37
Number of citations of the paper that reports this interaction (PubMedID
37219487
)
66
Data Source:
BioGRID
(unspecified method)
GABARAPL2
CDC37
Description
GABA type A receptor associated protein like 2
cell division cycle 37, HSP90 cochaperone
Image
GO Annotations
Cellular Component
Golgi Membrane
Autophagosome Membrane
Cytoplasm
Autophagosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Cytoplasmic Vesicle
Cytoplasm
Cytosol
Extracellular Exosome
Protein Folding Chaperone Complex
HSP90-CDC37 Chaperone Complex
Molecular Function
SNARE Binding
Protein Binding
Phospholipid Binding
Microtubule Binding
Phosphatidylethanolamine Binding
Ubiquitin Protein Ligase Binding
Beta-tubulin Binding
GABA Receptor Binding
ATPase Binding
Protein Binding
Protein Kinase Regulator Activity
Kinase Binding
Protein Kinase Binding
Heat Shock Protein Binding
Unfolded Protein Binding
Protein-folding Chaperone Binding
Hsp90 Protein Binding
Scaffold Protein Binding
Biological Process
Autophagosome Assembly
Mitophagy
Intra-Golgi Vesicle-mediated Transport
Autophagy
Cellular Response To Nitrogen Starvation
Protein Transport
Positive Regulation Of ATP-dependent Activity
Protein Localization To Endoplasmic Reticulum
Autophagosome Maturation
Negative Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Folding
Protein Targeting
Post-transcriptional Regulation Of Gene Expression
Protein Stabilization
Regulation Of Type II Interferon-mediated Signaling Pathway
Regulation Of Type I Interferon-mediated Signaling Pathway
Positive Regulation Of Type 2 Mitophagy
Pathways
Macroautophagy
TBC/RABGAPs
Signaling by ERBB2
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Constitutive Signaling by EGFRvIII
Regulation of necroptotic cell death
Downregulation of ERBB2 signaling
RHOBTB2 GTPase cycle
Constitutive Signaling by Overexpressed ERBB2
Drug-mediated inhibition of ERBB2 signaling
Signaling by ERBB2 KD Mutants
Resistance of ERBB2 KD mutants to trastuzumab
Resistance of ERBB2 KD mutants to sapitinib
Resistance of ERBB2 KD mutants to tesevatinib
Resistance of ERBB2 KD mutants to neratinib
Resistance of ERBB2 KD mutants to osimertinib
Resistance of ERBB2 KD mutants to afatinib
Resistance of ERBB2 KD mutants to AEE788
Resistance of ERBB2 KD mutants to lapatinib
Signaling by ERBB2 ECD mutants
Signaling by ERBB2 TMD/JMD mutants
Drug resistance in ERBB2 TMD/JMD mutants
Drugs
Diseases
GWAS
Age at first sexual intercourse (
34211149
)
Blood protein levels (
30072576
)
Pancreatic cancer (
25086665
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
LDL cholesterol levels in HIV infection (
33109212
)
Multiple sclerosis (
21833088
)
White blood cell count (
32888494
)
Interacting Genes
103 interacting genes:
AAMP
AGTRAP
AHNAK2
AMBRA1
ANK2
APP
APPL1
ARFGAP1
ATG13
ATG3
ATG4A
ATG4B
ATG4D
ATG7
AZI2
BCL2L13
BICC1
BNIP3L
BRD9
BSDC1
CALCOCO1
CALCOCO2
CARS2
CDC37
CEBPA
CLN8
CUL3
DYNLL1
DYNLL2
EGFR
ERBB2
ERBB3
ERBB4
FUNDC1
GIMAP6
GOSR1
GPR37
HAP1
INSYN1
KASH5
KBTBD6
KBTBD7
KIAA1958
KIF16B
KLHL5
KRTAP10-7
KRTAP10-9
LRSAM1
LZTR1
MAP4K2
MCPH1
MEF2A
MEFV
MLX
MRPL49
MYBPC1
NBR1
NCOR1
NEDD4
NPSR1
NSF
NUDT15
OPTN
OSBPL3
OSBPL7
PDLIM1
PTPRA
RAP1A
RAP2A
RB1CC1
RCN2
RESF1
RETREG1
RETREG3
RPS2
SCYL3
SEPTIN3
SGTA
SIK2
SMO
SQSTM1
TAX1BP1
TBC1D25
TBC1D5
TBC1D9
TBC1D9B
TEX264
TNIP1
TP53INP1
TP53INP2
TRIM21
TRIM25
TRIM32
TRIM45
TSR2
UBA5
ULK1
ULK2
VDR
WDFY3
YWHAZ
ZBTB2
ZNF774
182 interacting genes:
A2M
ACTB
ACTG1
AKT1
AMOTL2
APOE
APP
AR
BEND7
BLZF1
BTBD10
BTBD3
C19orf44
CAMK2A
CAMK2B
CAMK2G
CARD10
CARD9
CAVIN1
CBY2
CC2D1A
CCDC138
CCDC152
CCDC91
CCHCR1
CDC37L1
CDK2
CDK3
CDK4
CDK5
CDK6
CEP55
CEP70
CGGBP1
CHGA
CHUK
CKS1B
CKS2
CRYM
CSNK2A1
CSNK2A2
CT45A1
CTAG1A
CTAG1B
CUTC
CYP2C9
DCTN1
DEAF1
DISC1
DRC4
ECSIT
EIF2AK1
EIF2S1
ELAVL3
ENOX2
EXOSC1
FAM118A
FAM9B
FATE1
FBXL12
FBXW4
GABARAP
GABARAPL1
GABARAPL2
GAS7
GCDH
GCH1
GFAP
GMCL1
GOLGA2
GOLGA6L9
GPRASP3
GRAMD2B
GRIPAP1
HIVEP1
HOMER3
HSF2BP
HSP90AA1
IFIT5
IKBKB
IKBKE
IKBKG
IKZF3
IMMT
JRK
KATNBL1
KCTD13
KCTD9
KIFC3
KLHL2
KRT75
KRT76
LMNB2
LONP1
LOXL4
LUC7L2
LZTS1
MAD1L1
MAP1LC3A
MAP1LC3B
MAP1LC3C
MAP3K14
MAP3K3
MDFI
MID1
MIPOL1
MRPL9
MTOR
MZT2B
NCOA5
NECAB1
NECAB2
NOS3
NR2C2
NRIP3
NT5C1A
OGA
OGT
PAICS
PDE9A
PIBF1
PNMA2
POU6F2
PPHLN1
PPP5C
PRAM1
PRDX2
PRKAR1B
PRMT1
PRMT5
PRPH
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMC6
PSME1
PTGES3
RABGEF1
RAD23A
RAF1
REEP6
RNF32
ROPN1
RPS15A
SAFB
SEPTIN3
SNX5
SPTBN4
SQSTM1
SRRM4
SSNA1
STAMBPL1
STIP1
STK11
STX1A
SYCE2
SYCP3
TBK1
TCF4
THAP1
THAP7
TNFAIP1
TNIP1
TRAF2
TRAF3
TRAF5
TRIM54
UBE2I
USHBP1
WAC
ZBED1
ZBTB26
ZBTB8A
ZNF205
ZNF235
ZNF266
ZNF276
ZNF655
ZNF667
ZNF837
Entrez ID
11345
11140
HPRD ID
16246
05456
Ensembl ID
ENSG00000034713
ENSG00000105401
Uniprot IDs
P60520
Q16543
PDB IDs
4CO7
6H8C
7LK3
7YO8
8Q6Q
1US7
2K5B
2N5X
2NCA
2W0G
5FWK
5FWL
5FWM
5FWP
5HPE
7Z37
7Z38
7ZR0
7ZR5
7ZR6
8GAE
8GFT
8U1L
Enriched GO Terms of Interacting Partners
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Autophagosome
Autophagy
Macroautophagy
Autophagy Of Mitochondrion
Mitophagy
Autophagosome Assembly
Autophagosome Organization
Catabolic Process
Nucleophagy
Vacuole Organization
Piecemeal Microautophagy Of The Nucleus
Phagophore Assembly Site
Microautophagy
Positive Regulation Of Autophagy
Regulation Of Autophagy
Positive Regulation Of Catabolic Process
Cytosol
Reticulophagy
Cytoplasm
Aggrephagy
Cytoplasmic Vesicle
Intracellular Protein Localization
Organelle Assembly
Atg1/ULK1 Kinase Complex
Organelle Organization
Positive Regulation Of Macroautophagy
Protein Polyubiquitination
Regulation Of Intracellular Signal Transduction
Regulation Of Macroautophagy
Protein-phosphatidylethanolamide Deconjugating Activity
Autophagosome Membrane
Macromolecule Catabolic Process
Response To Stress
Regulation Of Signal Transduction
Protein Delipidation
Regulation Of Signaling
Receptor Complex
Protein Modification Process
Protein K48-linked Ubiquitination
Response To Mitochondrial Depolarisation
Protein Modification By Small Protein Conjugation
Positive Regulation Of Metabolic Process
Regulation Of Cell Communication
Establishment Of Protein Localization
Protein Binding
Phagophore Assembly Site Membrane
ERBB2 Signaling Pathway
Regulation Of MAPK Cascade
Protein Metabolic Process
Identical Protein Binding
Identical Protein Binding
Cytosol
Protein Binding
Cytoplasm
Cellular Response To Nitrogen Starvation
Mitophagy
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Protein Serine/threonine Kinase Activity
Phosphatidylethanolamine Binding
Autophagy Of Mitochondrion
Protein Serine Kinase Activity
Regulation Of Canonical NF-kappaB Signal Transduction
Organelle Organization
Macroautophagy
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Ubiquitin Protein Ligase Binding
Positive Regulation Of Signal Transduction
CD40 Receptor Complex
Protein Kinase Activity
Regulation Of Proteolysis
Regulation Of Intracellular Signal Transduction
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Localization To Membrane
Cyclin-dependent Protein Kinase Holoenzyme Complex
IkappaB Kinase Complex
Negative Regulation Of Translational Initiation
Microtubule Binding
Autophagy
Regulation Of Protein Localization To Cell Periphery
Regulation Of Signal Transduction
Intracellular Protein Localization
IkappaB Kinase Activity
Regulation Of Signaling
Regulation Of Cell Communication
Serine/threonine Protein Kinase Complex
Regulation Of Protein Catabolic Process
Kinase Activity
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Synaptic Transmission
Cellular Response To Nutrient Levels
Cellular Response To Starvation
Response To Starvation
Toll-like Receptor 4 Signaling Pathway
Regulation Of Protein Localization To Plasma Membrane
Anoikis
Positive Regulation Of TORC1 Signaling
Tau Protein Binding
Regulation Of Macroautophagy
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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