WIPF1 and FASTK

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		WIPF1	FASTK
Gene Name		WAS/WASL interacting protein family, member 1	Fas-activated serine/threonine kinase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Membrane-bounded Vesicle	Mitochondrion
	Molecular Function	Actin Binding Protein Binding Profilin Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity
	Biological Process	Protein Complex Assembly Actin Polymerization Or Depolymerization Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Response To Other Organism	Protein Phosphorylation Regulation Of RNA Splicing Apoptotic Signaling Pathway
Pathways		Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70	5 interactors: CALCOCO2 MDFI RBPMS TIA1 WIPF1
Entrez ID		7456	10922
HPRD ID		03835	07368
Ensembl ID		ENSG00000115935	ENSG00000164896
Uniprot IDs		O43516 Q2YDC4	Q14296
PDB IDs		2A41
Enriched GO Terms of Interacting Partners?		Immune Response-activating Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Locomotion Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Immune Response Phagocytosis Endocytosis Actin Filament Organization Regulation Of Cytoskeleton Organization Innate Immune Response Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Immune Response Axon Guidance Cell Motility Positive Regulation Of Immune System Process Positive Regulation Of Organelle Organization Actin Filament-based Process Regulation Of Actin Filament-based Process Neuron Projection Morphogenesis Neuron Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Vesicle-mediated Transport Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Organization Neuron Differentiation Axonogenesis Cell Projection Organization Cell Projection Morphogenesis Axon Development Cell Part Morphogenesis Actin Polymerization Or Depolymerization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Organelle Organization Immune System Process Immune Response	Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport
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