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WIPF1 and WASL
Number of citations of the paper that reports this interaction (PubMedID
16055720
)
76
Data Source:
HPRD
(in vitro, in vivo)
WIPF1
WASL
Description
WAS/WASL interacting protein family member 1
WASP like actin nucleation promoting factor
Image
GO Annotations
Cellular Component
Ruffle
Cytoplasm
Cytosol
Cytoskeleton
Actin Filament
Actin Cytoskeleton
Cytoplasmic Vesicle
Cell Projection
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Cytoskeleton
Plasma Membrane
Actin Cytoskeleton
Lamellipodium
Actin Cap
Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Actin Binding
Protein Binding
Profilin Binding
Cytoskeletal Anchor Activity
SH3 Domain Binding
Protein Folding Chaperone
Actin Binding
Protein Binding
GTPase Regulator Activity
Biological Process
Protein Folding
Actin Polymerization Or Depolymerization
Actin Filament-based Process
Actin Filament-based Movement
Response To Other Organism
Protein-containing Complex Assembly
Vesicle Budding From Membrane
Actin Filament Organization
Actin Polymerization Or Depolymerization
Response To Bacterium
Vesicle Organization
Actin Cytoskeleton Organization
Actin Filament Polymerization
Vesicle Transport Along Actin Filament
Protein-containing Complex Localization
Regulation Of Protein Localization
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Filopodium Assembly
Spindle Localization
Dendritic Spine Morphogenesis
Protein-containing Complex Assembly
Regulation Of Postsynapse Organization
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of Lymphocyte Migration
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
CDC42 GTPase cycle
RAC1 GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
NOSTRIN mediated eNOS trafficking
Nephrin family interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
DCC mediated attractive signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
CDC42 GTPase cycle
RAC1 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RHOV GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Atrial fibrillation (
29892015
30061737
)
Mean platelet volume (
32888494
)
Platelet distribution width (
32888494
)
Pulse pressure (
27841878
)
Resting heart rate (
27798624
)
Systolic blood pressure (
27841878
)
Urate levels (BMI interaction) (
25811787
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Platelet count (
22139419
27863252
)
Plateletcrit (
27863252
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
26 interacting genes:
ABI2
ACTC1
ACTG1
ALAS1
APBB1
CACNG2
CDC42
CEBPA
CRKL
CTTN
FASTK
GRB2
HCK
HOMER3
ITSN2
NCK1
PRKCQ
PRPF40A
RER1
SEC24C
SH3RF1
WAS
WASL
WBP4
WWP2
ZAP70
62 interacting genes:
ABI2
ABL1
ACTG1
ACTR2
ACTR3
APBB1
APP
ARPC3
ARPC4
BIN1
CDC42
CORO7
CTTN
DNMBP
EGFR
EVL
FCHSD2
FNBP1
FNBP1L
GRB2
HP
HSP90AA1
HSP90AB1
IPO5
ITCH
ITGB1BP2
ITSN1
ITSN2
LCK
NCK1
NCK2
NCKIPSD
OSTF1
PACSIN1
PACSIN2
PACSIN3
PFN1
PRMT2
PRPF40A
PSTPIP1
PTK6
RHOQ
RIPPLY3
RNF8
RPL7AP66
SDCBP
SH3GL3
SH3RF1
SNX9
SORBS2
SRC
TNNT3
TRIP10
UBASH3A
UBASH3B
VASP
VIPR1
WIPF1
WIPF2
WIPF3
WWP1
ZNF395
Entrez ID
7456
8976
HPRD ID
03835
05448
Ensembl ID
ENSG00000115935
ENSG00000106299
Uniprot IDs
A0A140VJZ9
E9PB87
O43516
Q2YDC4
O00401
PDB IDs
2A41
9EZN
9EZO
9EZP
2FF3
2LNH
2VCP
4CC2
4CC7
9DLX
Enriched GO Terms of Interacting Partners
?
Actin Filament
Regulation Of Actin Filament Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament-based Process
Regulation Of Supramolecular Fiber Organization
Cell Motility
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Cytoskeleton Organization
Lamellipodium
Cell-cell Junction
Phosphotyrosine Residue Binding
Positive Regulation Of Actin Filament Polymerization
Regulation Of Cytoskeleton Organization
Actin Filament-based Process
Actin Filament Organization
Proline-rich Region Binding
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Cell Projection Morphogenesis
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Migration
Cytosol
Regulation Of Cell Projection Organization
Positive Regulation Of Protein Polymerization
Positive Regulation Of Organelle Organization
Positive Regulation Of Cellular Component Biogenesis
Actin Cytoskeleton Organization
Dendritic Spine Organization
Cell Projection Organization
Regulation Of Cell Projection Assembly
Regulation Of Lamellipodium Assembly
Vesicle Membrane
Regulation Of Cellular Component Organization
Positive Regulation Of Cellular Component Organization
Intracellular Signaling Cassette
Immune Response-regulating Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Neuron Projection Organization
Regulation Of Cellular Component Size
Regulation Of Actin Filament Polymerization
Postsynapse Organization
Neuron Projection Morphogenesis
Regulation Of Organelle Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Small GTPase-mediated Signal Transduction
Cell Junction Organization
Peptidyl-tyrosine Phosphorylation
Regulation Of Lamellipodium Organization
Regulation Of Immune System Process
Antigen Receptor-mediated Signaling Pathway
Endocytosis
Actin Filament Organization
Positive Regulation Of Cellular Component Biogenesis
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Actin Filament Polymerization
Import Into Cell
Positive Regulation Of Cellular Component Organization
Supramolecular Fiber Organization
Cytoplasm
Cytosol
Positive Regulation Of Protein Polymerization
Regulation Of Actin Filament Organization
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Regulation Of Cellular Component Organization
Profilin Binding
Regulation Of Actin Filament-based Process
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament Polymerization
Actin Filament-based Process
Positive Regulation Of Cell Projection Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Endocytosis
Positive Regulation Of Protein-containing Complex Assembly
Vesicle-mediated Transport
Regulation Of Cell Projection Organization
Cytoskeleton Organization
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Organelle Organization
Actin Cytoskeleton Organization
Regulation Of Cytoskeleton Organization
Lamellipodium
Regulation Of Cellular Component Size
Cytoskeletal Anchor Activity
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Cell Projection
Focal Adhesion
Regulation Of Cell Projection Assembly
Cytoskeleton
Plasma Membrane Tubulation
Actin Polymerization Or Depolymerization
Positive Regulation Of Lamellipodium Organization
Proline-rich Region Binding
Arp2/3 Complex-mediated Actin Nucleation
Extracellular Exosome
SH3 Domain Binding
Regulation Of Vesicle-mediated Transport
Actin Binding
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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