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WIPF1 and WWP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
WIPF1
WWP2
Gene Name
WAS/WASL interacting protein family, member 1
WW domain containing E3 ubiquitin protein ligase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Cytosol
Actin Filament
Actin Cytoskeleton
Cytoplasmic Membrane-bounded Vesicle
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Membrane
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
Protein Binding
Profilin Binding
RNA Polymerase II Transcription Factor Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Ligase Activity
Biological Process
Protein Complex Assembly
Actin Polymerization Or Depolymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Response To Other Organism
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Transporter Activity
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Negative Regulation Of Protein Transport
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
IgE levels (
23146381
)
Protein-Protein Interactions
22 interactors:
ABI2
ACTC1
ACTG1
ALAS1
APBB1
CDC42
CRKL
CTTN
FASTK
GRB2
HCK
HOMER3
ITSN2
NCK1
PRKCQ
PRPF40A
SEC24C
WAS
WASL
WBP4
WWP2
ZAP70
53 interactors:
ANKRD44
ARRDC1
ATN1
CDC34
CLCN5
CPSF6
DAG1
DIDO1
EGR2
EWSR1
FAM189A2
FBXL18
HNRNPUL1
IL2RG
IL6R
LGALS9B
NDFIP2
PAIP1
PDLIM7
POLR2A
POU5F1
RASA1
RNF11
RUSC1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SF1
SFTPC
SMAD3
SMAD7
SNRPC
SPG20
TFAP2A
TNK2
TP53BP2
TRAF4
UBC
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2J2
UBE2K
UBE2L3
USP7
VASP
VPS37C
WBP1
WBP2
WIPF1
Entrez ID
7456
11060
HPRD ID
03835
03812
Ensembl ID
ENSG00000115935
ENSG00000198373
Uniprot IDs
O43516
Q2YDC4
B4DHF6
O00308
PDB IDs
2A41
Enriched GO Terms of Interacting Partners
?
Immune Response-activating Cell Surface Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Locomotion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-regulating Signaling Pathway
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Immune Response
Phagocytosis
Endocytosis
Actin Filament Organization
Regulation Of Cytoskeleton Organization
Innate Immune Response
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Neuron Projection Development
Regulation Of Actin Cytoskeleton Organization
Cell Migration
Actin Cytoskeleton Organization
Positive Regulation Of Actin Nucleation
Regulation Of Immune Response
Axon Guidance
Cell Motility
Positive Regulation Of Immune System Process
Positive Regulation Of Organelle Organization
Actin Filament-based Process
Regulation Of Actin Filament-based Process
Neuron Projection Morphogenesis
Neuron Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Vesicle-mediated Transport
Cytoskeleton Organization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cellular Component Organization
Neuron Differentiation
Axonogenesis
Cell Projection Organization
Cell Projection Morphogenesis
Axon Development
Cell Part Morphogenesis
Actin Polymerization Or Depolymerization
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Organelle Organization
Immune System Process
Immune Response
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Response To Stimulus
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Excretion
Response To Organic Substance
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Protein K11-linked Ubiquitination
Sodium Ion Homeostasis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Gene Expression
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stimulus
Positive Regulation Of Ossification
Regulation Of Ossification
RNA Biosynthetic Process
Regulation Of Protein Ubiquitination
Apoptotic Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Regulation Of Cellular Protein Metabolic Process
Viral Process
Apoptotic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Protein Catabolic Process
RNA Processing
Multicellular Organismal Water Homeostasis
Programmed Cell Death
Negative Regulation Of Transcription By Competitive Promoter Binding
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Proteolysis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Difference)
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Intersection)
?