SFPQ and TCERG1

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		SFPQ	TCERG1
Gene Name		splicing factor proline/glutamine-rich	transcription elongation regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Paraspeckles	Nucleus Nucleolus Actin Cytoskeleton
	Molecular Function	Nucleotide Binding Transcription Regulatory Region Sequence-specific DNA Binding Core Promoter Binding Protein Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding	RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Transcription Coactivator Activity Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Alternative MRNA Splicing, Via Spliceosome DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Histone H3 Deacetylation Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Endometrial cancer ( 21499250)
Protein-Protein Interactions		27 interactors: APBB1 AR CSNK2A1 ERG EXOSC5 FHL2 FUS GAS7 HIST3H3 HN1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC WBP4 ZMYM2	52 interactors: ABI1 BARD1 BRD4 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO1 TPM4 U2AF2 WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		6421	10915
HPRD ID		07284	10393
Ensembl ID		ENSG00000116560	ENSG00000113649
Uniprot IDs		P23246 Q86VG2	O14776
PDB IDs			2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2NNT 3HFH 4FQG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of Circadian Rhythm RNA Splicing MRNA Metabolic Process Transcription, DNA-templated MRNA Processing RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Apoptotic Process RNA Processing Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Circadian Rhythm Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Cycle Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Biosynthetic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process MRNA 3'-splice Site Recognition Cellular Component Assembly MRNA Splice Site Selection Spliceosomal Complex Assembly Regulation Of RNA Splicing Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Cellular Metabolic Process Protein Complex Assembly Cellular Process Positive Regulation Of RNA Splicing Cellular Response To Stress Regulation Of MRNA Processing Actin Polymerization Or Depolymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To DNA Damage Stimulus Response To Stress DNA Repair Ribonucleoprotein Complex Biogenesis Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Transcription, DNA-templated Viral Process Phagocytosis Regulation Of Gene Expression Fc Receptor Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process MRNA 3'-end Processing Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Lamellipodium Morphogenesis Rhythmic Process Developmental Process
Tagcloud ?			12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Difference) ?			12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Intersection) ?