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DHX15
Gene Name
DEAH (Asp-Glu-Ala-His) box helicase 15
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
U12-type Spliceosomal Complex
Nucleolus
Cytoplasm
U2-type Post-mRNA Release Spliceosomal Complex
Molecular Function
RNA Helicase Activity
Double-stranded RNA Binding
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Pathways
Drugs
Diseases
GWAS
Myopia (pathological) (
23049088
)
Protein-protein Interactions
12 interactors:
APBB1
DDX42
NKAP
PIN1
PINX1
PRPF40A
RBM17
TRA2A
WBP4
YWHAB
YWHAG
ZGPAT
Entrez ID
1665
HPRD ID
04553
Ensembl ID
ENSG00000109606
Uniprot IDs
O43143
PDB IDs
Enriched GO Terms of Interacting Partners
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RNA Splicing
MRNA Processing
Gene Expression
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
MRNA Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Biosynthetic Process
Cell Cycle
RNA Metabolic Process
Positive Regulation Of Mitochondrion Organization
Regulation Of Cytokinesis
Negative Regulation Of Transferase Activity
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Phosphorylation
Regulation Of Mitochondrion Organization
Regulation Of Protein Phosphorylation
Nitrogen Compound Metabolic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Regulation Of Phosphorylation
Positive Regulation Of Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Catalytic Activity
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Cellular Metabolic Process
Cellular Response To Insulin Stimulus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Regulation Of Protein Kinase Activity
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Kinase Activity
Negative Regulation Of Catalytic Activity
Positive Regulation Of Intracellular Transport
Regulation Of Kinase Activity
Negative Regulation Of Cellular Protein Metabolic Process
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