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DHX15 and PIN1
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
DHX15
PIN1
Gene Name
DEAH (Asp-Glu-Ala-His) box helicase 15
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
U12-type Spliceosomal Complex
Nucleolus
Cytoplasm
U2-type Post-mRNA Release Spliceosomal Complex
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Midbody
Molecular Function
RNA Helicase Activity
Double-stranded RNA Binding
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
Mitogen-activated Protein Kinase Kinase Binding
GTPase Activating Protein Binding
Phosphoserine Binding
Phosphothreonine Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Protein Peptidyl-prolyl Isomerization
Positive Regulation Of Protein Phosphorylation
Cell Cycle
Regulation Of Mitotic Nuclear Division
Cytokine-mediated Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Rho GTPase Activity
Regulation Of Cytokinesis
Negative Regulation Of Type I Interferon Production
Innate Immune Response
Positive Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Cell Motility
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Negative regulators of RIG-I/MDA5 signaling
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Antiviral mechanism by IFN-stimulated genes
Innate Immune System
Drugs
Diseases
GWAS
Myopia (pathological) (
23049088
)
Protein-Protein Interactions
12 interactors:
APBB1
DDX42
NKAP
PIN1
PINX1
PRPF40A
RBM17
TRA2A
WBP4
YWHAB
YWHAG
ZGPAT
184 interactors:
ABI2
ADAMTSL4
ADARB1
AMOT
ANKRD40
AP2A1
APLP1
APP
ARHGEF15
ATP5B
BAG6
BCL2
BCL6
BCLAF1
CAPRIN1
CARHSP1
CASP6
CBS
CCDC184
CCDC33
CCDC90B
CCNB1
CCNE1
CCNK
CDC25C
CDC27
CDK1
CDK11A
CDK11B
CDK12
CDK2
CDK9
CDKN1B
CENPB
CEP55
CEP76
CHAMP1
CHPF
CNKSR1
COL11A2
CPNE6
CSAD
CSNK2A1
CSNK2A2
CSNK2B
CTNNB1
DAB1
DAB2
DDAH2
DDB1
DDX17
DDX24
DDX3X
DDX5
DEAF1
DHX15
DMPK
DYNC1I1
EFTUD2
EIF3G
EP300
ETV6
FASLG
FOXO4
FOXP2
G3BP1
G3BP2
GGA2
GOLGA2
GPAA1
GPHN
HADHA
HEXIM2
HNRNPC
HNRNPH1
HNRNPK
HNRNPU
HOMEZ
IKZF1
IKZF3
JAKMIP2
JUN
KIAA1429
KIF20B
KIF5A
KLHL20
KMT2B
KRT31
KRT38
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP4-2
LEPR
LRIF1
MAP1S
MAP3K11
MAPT
MCL1
MDFI
MED1
MEOX2
MOCS1
MTFR1
MTUS2
MYT1
NAB2
NCOA3
NEK6
NFATC2
NONO
NUP62
PABPC1
PKIB
PKM
PKMYT1
PLK1
PML
PNMA1
POLR2A
PRPF8
PRRC1
PTOV1
PTPN1
QARS
RAB4A
RAF1
RAI1
RARA
RBBP8
RBPMS
RELA
REPS1
RNPS1
RPL4
RPS6KB1
SFPQ
SHKBP1
SMAD3
SNRNP200
SOCS3
SPERT
SREK1
SRRM1
SRRM2
SRSF11
SSBP3
STIL
SUPT5H
TAB3
TBC1D4
TCF4
TFG
THAP7
THRAP3
TLE3
TNIP1
TOP2A
TP53
TP73
TRAF1
TRAF2
TRIP6
TRMT2A
TSC2
TSC22D4
TUT1
U2AF2
UBB
UBQLN4
UNC119
WEE1
WIZ
WRNIP1
XRCC6
ZBTB14
ZBTB22
ZBTB7B
ZBTB9
ZCCHC10
ZMIZ2
ZNF446
Entrez ID
1665
5300
HPRD ID
04553
03031
Ensembl ID
ENSG00000109606
ENSG00000127445
Uniprot IDs
O43143
Q13526
PDB IDs
1F8A
1I6C
1I8G
1I8H
1NMV
1NMW
1PIN
1ZCN
2F21
2ITK
2KBU
2KCF
2LB3
2M9E
2M9F
2M9I
2M9J
2Q5A
2XP3
2XP4
2XP5
2XP6
2XP7
2XP8
2XP9
2XPA
2XPB
2ZQS
2ZQT
2ZQU
2ZQV
2ZR4
2ZR5
2ZR6
3I6C
3IK8
3IKD
3IKG
3JYJ
3KAB
3KAC
3KAD
3KAF
3KAG
3KAH
3KAI
3KCE
3NTP
3ODK
3OOB
3TC5
3TCZ
3TDB
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Processing
Gene Expression
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
MRNA Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Biosynthetic Process
Cell Cycle
RNA Metabolic Process
Positive Regulation Of Mitochondrion Organization
Regulation Of Cytokinesis
Negative Regulation Of Transferase Activity
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Phosphorylation
Regulation Of Mitochondrion Organization
Regulation Of Protein Phosphorylation
Nitrogen Compound Metabolic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Regulation Of Phosphorylation
Positive Regulation Of Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Catalytic Activity
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Cellular Metabolic Process
Cellular Response To Insulin Stimulus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Regulation Of Protein Kinase Activity
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Kinase Activity
Negative Regulation Of Catalytic Activity
Positive Regulation Of Intracellular Transport
Regulation Of Kinase Activity
Negative Regulation Of Cellular Protein Metabolic Process
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Mitotic Cell Cycle
RNA Processing
Mitotic Cell Cycle Process
Regulation Of Mitotic Cell Cycle
Cell Death
Death
Negative Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
MRNA Processing
Cell Cycle Process
Regulation Of Nucleic Acid-templated Transcription
Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Cell Cycle Process
Negative Regulation Of Biosynthetic Process
Cell Cycle
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Gene Expression
Programmed Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Apoptotic Process
MRNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Protein Phosphorylation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Phosphorylation
Tagcloud
?
13c
15n
1h
1hn
affinities
aliphatic
assignment
backbone
betap2
complexed
detects
developmentally
enac
isomerase
nedd4
owing
peptidyl
ppxy
proline
prolyl
py
resonances
rnedd4
sequential
shifts
virtually
ww
yap65
yes
Tagcloud (Difference)
?
13c
15n
1h
1hn
affinities
aliphatic
assignment
backbone
betap2
complexed
detects
developmentally
enac
isomerase
nedd4
owing
peptidyl
ppxy
proline
prolyl
py
resonances
rnedd4
sequential
shifts
virtually
ww
yap65
yes
Tagcloud (Intersection)
?