CHD3 and PTPRS

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	PTPRS
Gene Name		chromodomain helicase DNA binding protein 3	protein tyrosine phosphatase, receptor type, S
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization	Cell Adhesion Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Extracellular Matrix Organization Peptidyl-tyrosine Dephosphorylation
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance	ECM proteoglycans
Drugs
Diseases
GWAS
Protein-Protein Interactions		90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1	23 interactors: CHD3 EEF1G EGFR FEZ1 KAT5 KIAA1377 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 TUBB2A UBR1 UNC119 UTP14A
Entrez ID		1107	5802
HPRD ID		09071	03344
Ensembl ID		ENSG00000170004	ENSG00000105426
Uniprot IDs		B3KWV4 Q12873 Q2TAZ1	Q13332 Q59FX6 Q8NHS7
PDB IDs			2FH7 2YD2 2YD3 2YD9 4BPC
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Glutamate Secretion Protein Dephosphorylation Acid Secretion Dephosphorylation Dicarboxylic Acid Transport Neurotransmitter Secretion Cellular Response To Estradiol Stimulus Regulation Of Neurotransmitter Levels Cellular Response To Estrogen Stimulus Positive Regulation Of Vasodilation Axon Guidance Amino Acid Transport Neuron Differentiation Neurotransmitter Transport Cell Projection Organization Signaling Cell Adhesion Cell Communication Regulation Of Vasodilation Neuron Projection Development Negative Regulation Of Epithelial Cell Migration Response To Estrogen Cell Projection Morphogenesis Cellular Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Cell Part Morphogenesis Secretion By Cell Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Cellular Response To Organic Substance Cell-cell Signaling Axonogenesis Cellular Response To Amino Acid Stimulus Regulation Of Stress Fiber Assembly Neuron Development Cellular Protein Modification Process Axon Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Astrocyte Activation Dense Core Granule Maturation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Regulation Of Dendrite Morphogenesis Chemotaxis Cell Cycle Process
Tagcloud ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Difference) ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Intersection) ?