PTPRS and RAB35

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PTPRS	RAB35
Gene Name		protein tyrosine phosphatase, receptor type, S	RAB35, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Golgi Membrane Mitochondrion Endoplasmic Reticulum Membrane Plasma Membrane Coated Pit Endosome Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process	Cell Adhesion Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Extracellular Matrix Organization Peptidyl-tyrosine Dephosphorylation	Cytokinesis Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein Localization Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		ECM proteoglycans
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: CHD3 EEF1G EGFR FEZ1 KAT5 KIAA1377 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 TUBB2A UBR1 UNC119 UTP14A	7 interactors: APP C2orf44 CBR3 GNPAT IDH3B PTPRS TBPL1
Entrez ID		5802	11021
HPRD ID		03344	05010
Ensembl ID		ENSG00000105426	ENSG00000111737
Uniprot IDs		Q13332 Q59FX6 Q8NHS7	G5E9K9 Q15286
PDB IDs		2FH7 2YD2 2YD3 2YD9 4BPC	3TW8
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Glutamate Secretion Protein Dephosphorylation Acid Secretion Dephosphorylation Dicarboxylic Acid Transport Neurotransmitter Secretion Cellular Response To Estradiol Stimulus Regulation Of Neurotransmitter Levels Cellular Response To Estrogen Stimulus Positive Regulation Of Vasodilation Axon Guidance Amino Acid Transport Neuron Differentiation Neurotransmitter Transport Cell Projection Organization Signaling Cell Adhesion Cell Communication Regulation Of Vasodilation Neuron Projection Development Negative Regulation Of Epithelial Cell Migration Response To Estrogen Cell Projection Morphogenesis Cellular Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Cell Part Morphogenesis Secretion By Cell Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Cellular Response To Organic Substance Cell-cell Signaling Axonogenesis Cellular Response To Amino Acid Stimulus Regulation Of Stress Fiber Assembly Neuron Development Cellular Protein Modification Process Axon Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Astrocyte Activation Dense Core Granule Maturation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Regulation Of Dendrite Morphogenesis Chemotaxis Cell Cycle Process	Small Molecule Metabolic Process Synapse Assembly Phosphate-containing Compound Metabolic Process Cerebellum Development Metencephalon Development Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Phylloquinone Catabolic Process Hindbrain Development Synapse Organization Brain Development DTTP Biosynthetic Process Cellular Component Assembly Head Development Collateral Sprouting Axon Midline Choice Point Recognition Ether Lipid Biosynthetic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Ketone Catabolic Process Central Nervous System Development Isocitrate Metabolic Process Organophosphate Metabolic Process Neuron Remodeling Ether Lipid Metabolic Process Cognition Deoxyribonucleotide Biosynthetic Process Acrosome Assembly Cofactor Metabolic Process 2-oxoglutarate Metabolic Process Corpus Callosum Development NADH Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Paranodal Junction Assembly Cellular Copper Ion Homeostasis Glycerol Ether Metabolic Process Copper Ion Homeostasis Suckling Behavior Forebrain Development Deoxyribonucleoside Triphosphate Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Spermatid Nucleus Differentiation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Myelin Assembly Mating Behavior
Tagcloud ?		cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab1 rab1a rab33 rab41 rab6a rabs rbd35 rufy2 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Difference) ?		cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab1 rab1a rab33 rab41 rab6a rabs rbd35 rufy2 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Intersection) ?