CHD3 and FBP2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	FBP2
Gene Name		chromodomain helicase DNA binding protein 3	fructose-1,6-bisphosphatase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton	Nucleus Cytosol Z Disc Cell Junction Extracellular Vesicular Exosome
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Fructose 1,6-bisphosphate 1-phosphatase Activity Metal Ion Binding
	Biological Process	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization	Carbohydrate Metabolic Process Fructose Metabolic Process Glucose Metabolic Process Gluconeogenesis Pathogenesis Dephosphorylation Small Molecule Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS			Height ( 19893584)
Protein-Protein Interactions		90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1	2 interactors: CHD3 FBP1
Entrez ID		1107	8789
HPRD ID		09071	04322
Ensembl ID		ENSG00000170004	ENSG00000130957
Uniprot IDs		B3KWV4 Q12873 Q2TAZ1	O00757
PDB IDs			3IFA 3IFC
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process	Cellular Response To Magnesium Ion Negative Regulation Of Glycolytic Process Fructose Metabolic Process Response To Magnesium Ion Fructose 6-phosphate Metabolic Process Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Gluconeogenesis Cellular Response To Drug Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Hexose Biosynthetic Process Protein Homotetramerization Regulation Of Generation Of Precursor Metabolites And Energy DNA Duplex Unwinding DNA Geometric Change Centrosome Organization Protein Tetramerization Regulation Of Glucose Metabolic Process Microtubule Organizing Center Organization Spindle Organization Cellular Response To Metal Ion Cellular Response To Inorganic Substance Glucose Metabolic Process Chromatin Assembly Or Disassembly Regulation Of Carbohydrate Metabolic Process Carbohydrate Biosynthetic Process Negative Regulation Of Cell Growth
Tagcloud ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	add2 adducin altering chimeric compete competition cryptic distal dse emsa fbp1 helicase hexanucleotide hm immediately minigenes nucleolin pas polyadenylation processed ptb pull repeats subcellular tight transfections translability ug vigilin
Tagcloud (Difference) ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	add2 adducin altering chimeric compete competition cryptic distal dse emsa fbp1 helicase hexanucleotide hm immediately minigenes nucleolin pas polyadenylation processed ptb pull repeats subcellular tight transfections translability ug vigilin
Tagcloud (Intersection) ?