PTPRS and PTPRE

Number of citations of the paper that reports this interaction (PubMedID 12376545)
0

Data Source:
HPRD (in vivo)

		PTPRS	PTPRE
Description		protein tyrosine phosphatase receptor type S	protein tyrosine phosphatase receptor type E
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Postsynaptic Density Membrane Axon Growth Cone Synaptic Vesicle Membrane Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Neuron Projection Perikaryon Synapse Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Cytoplasm Plasma Membrane Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Heparin Binding Hydrolase Activity Chondroitin Sulfate Binding Heparan Sulfate Proteoglycan Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Identical Protein Binding
	Biological Process	Protein Dephosphorylation Cell Adhesion Signal Transduction Negative Regulation Of Neuron Projection Development Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Negative Regulation Of Axon Extension Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Modulation Of Chemical Synaptic Transmission Synapse Organization Negative Regulation Of Dendritic Spine Development Establishment Of Endothelial Intestinal Barrier Regulation Of Postsynaptic Density Assembly Trans-synaptic Signaling Synaptic Membrane Adhesion	Protein Dephosphorylation Signal Transduction Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Regulation Of Mast Cell Activation Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		ECM proteoglycans Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules Signaling by NTRK3 (TRKC)
Drugs		Alendronic acid Etidronic acid	Alendronic acid Tiludronic acid
Diseases
GWAS		Thyroid stimulating hormone levels ( 32769997) Type 2 diabetes ( 30297969) Waist-hip ratio ( 28552196)	Response to amphetamines ( 22952603) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		28 interacting genes: CEP126 CHD3 EEF1G EGFR FEZ1 GPC2 GPC3 GPC6 KAT5 MOB4 OMG PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 SLITRK1 TUBB2A UBR1 UNC119 UTP14A	10 interacting genes: FYN GRB2 KCNA5 KCNB1 MAPK1 MAPK3 PTPRD PTPRS SRC YES1
Entrez ID		5802	5791
HPRD ID		03344	02956
Ensembl ID		ENSG00000105426	ENSG00000132334
Uniprot IDs		Q13332 Q59FX6 Q8NHS7	A8K2Z9 P23469 Q96P81
PDB IDs		2FH7 2YD2 2YD3 2YD9 4BPC 4PBX	2JJD 6D3F 6D4D 6D4F
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Phosphatase Activity Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Protein Tyrosine Phosphatase Activity Regulation Of Protein Localization To Membrane Schaffer Collateral - CA1 Synapse Regulation Of Cellular Component Organization Cell Adhesion Side Of Membrane Synapse Organization Presynaptic Active Zone Regulation Of Neuron Projection Development Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphoprotein Phosphatase Activity Regulation Of Cell Projection Organization Positive Regulation Of Neuron Projection Development Regulation Of Cellular Localization Glutamatergic Synapse Positive Regulation Of Cell Projection Organization Regulation Of Stem Cell Differentiation Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cellular Component Organization Lysosomal Lumen Presynapse Organization Intercellular Bridge Positive Regulation Of Peptidyl-serine Phosphorylation Golgi Lumen Synapse Synaptic Membrane Adhesion Microtubule Cytoskeleton Organization Cell Junction Organization Neuron Projection Regeneration Neuron Projection Development Regulation Of Peptidyl-serine Phosphorylation Modulation Of Chemical Synaptic Transmission Cellular Response To Estradiol Stimulus Multivesicular Body, Internal Vesicle Lumen Peptidyl-dipeptidase Inhibitor Activity Cell Projection Organization Structural Constituent Of Presynapse Epididymosome Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Histone H2AK5 Acetyltransferase Activity	Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Response To Growth Factor Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response T Cell Costimulation Phosphotyrosine Residue Binding Cellular Response To Transforming Growth Factor Beta Stimulus Epidermal Growth Factor Receptor Signaling Pathway Response To Transforming Growth Factor Beta Caveola ERBB Signaling Pathway Negative Regulation Of Immune Response Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Regulation Of Defense Response Cellular Response To Platelet-derived Growth Factor Stimulus Modulation Of Chemical Synaptic Transmission Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Immune Response-activating Cell Surface Receptor Signaling Pathway ERBB2 Signaling Pathway Protein Kinase Activity Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Negative Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Ephrin Receptor Binding Regulation Of Multicellular Organismal Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Interleukin-34-mediated Signaling Pathway Protein Tyrosine Kinase Activity Insulin-like Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Kinase Activity Regulation Of Immune System Process Transmembrane Transporter Binding Signal Transduction Protein Phosphorylation Immune Response-activating Signaling Pathway Regulation Of Golgi Inheritance Non-membrane Spanning Protein Tyrosine Kinase Activity Plasma Membrane Phosphorylation Regulation Of Leukocyte Cell-cell Adhesion Regulation Of T Cell Activation Immune Effector Process Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Signaling Receptor Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?