CHD3 and SAT1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	SAT1
Gene Name		chromodomain helicase DNA binding protein 3	spermidine/spermine N1-acetyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton	Intracellular Cytosol
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Diamine N-acetyltransferase Activity Protein Binding Spermidine Binding
	Biological Process	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization	Angiogenesis Polyamine Metabolic Process Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Small Molecule Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance	Metabolism of polyamines Interconversion of polyamines Metabolism of amino acids and derivatives
Drugs			N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS
Protein-Protein Interactions		90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1	75 interactors: ABCB8 APLP1 B4GALT3 C14orf1 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DMRT3 DNPEP EEF1G EIF3D EPHB6 EVA1A FAM156A FAM69B FAM86C1 FTSJ3 FUNDC2 GBP2 GDF9 GNB2L1 HIF1A HOXB6 HOXB9 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KIAA1377 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1
Entrez ID		1107	6303
HPRD ID		09071	02431
Ensembl ID		ENSG00000170004	ENSG00000130066
Uniprot IDs		B3KWV4 Q12873 Q2TAZ1	P21673 Q6ICU9
PDB IDs			2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process	RNA Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of RNA Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Response To External Stimulus Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Response To Light Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Locomotion Regulation Of Interleukin-12 Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Axon Guidance Response To Abiotic Stimulus
Tagcloud ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Difference) ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Intersection) ?