CHD3 and GPS2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHD3	GPS2
Gene Name		chromodomain helicase DNA binding protein 3	G protein pathway suppressor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton	Nucleoplasm Transcriptional Repressor Complex
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Transcription Corepressor Activity GTPase Inhibitor Activity Protein Binding
	Biological Process	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Inactivation Of MAPK Activity Chromatin Organization Cell Cycle JNK Cascade Negative Regulation Of JNK Cascade
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance	Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1	23 interactors: ATF4 C19orf57 CCNA1 CHD3 CNOT2 EP300 GOLGA2 HDAC1 HDAC3 KRT31 MAP3K7CL NCOR1 NR0B2 PBK RALBP1 RBPMS SESTD1 SETDB1 SPDL1 TBL1X TBL1XR1 TFIP11 TP53
Entrez ID		1107	2874
HPRD ID		09071	11878
Ensembl ID		ENSG00000170004	ENSG00000132522
Uniprot IDs		B3KWV4 Q12873 Q2TAZ1	Q13227
PDB IDs			2L5G
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process	Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromosome Organization Transcription, DNA-templated Circadian Rhythm Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Rhythmic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Cellular Metabolic Process Circadian Regulation Of Gene Expression Regulation Of Gene Expression Histone Modification Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cell Cycle Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Organelle Organization Nucleobase-containing Compound Metabolic Process Histone H3-K9 Modification Regulation Of Metabolic Process Negative Regulation Of Stress-activated MAPK Cascade Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process
Tagcloud ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Difference) ?		ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous	abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Intersection) ?